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Effects of patency of infarct-related coronary artery on acute outcome in acute myocardial infarction patients undergoing urokinase therapy

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收录情况： ◇ SCIE ◇ 中华系列

作者：
Chen Zaijia[1] * ; Kou Wenrong [1] ; Xu Yishu[1] ; Zhang Guozhu[2] ; Wang Yiping[2] ; Mu Ruiqi[3] ; Du Ming[3] ; Chen Changxi[4] ; Huang Jianqun[4] ; Guo Jing xuan[5] ; Ge Kanyi[5] ; Shi Jialing [6] ; Sun Yuemin[6] ; Duan Baoxiang[7] ; Gong Hehe[7] ; Li Guijun[8] ; Wang Lemin[8] ; Huang Yonglin[9] ; Fu Lu[9] ; Shen Luhua[10] ; Yang Jiasheng[10] ; Tong Ming [11] ; Hu Xiaoling[11] ; Liu Ruiy un [12] ; Cun Zhicheng[12] ; Wu Xuesi[13] ; Chen Zhan[13] ; Li Tiande[14] ; Gai Luyu[14] ; Li Yunqian [15] ; Liu Zhuomin[15] ; Shi Shuying [16] ; Tang Zhe[16] ; Gao Binxin[17] ; Liu Zhaox i[17] ; Li Yan[18] ; Zhang Juxia[18] ; Zhao Huayue[19] ; Wang Lin[19] ; Wang Shiguang[20] ; Chi Chuanfu[20] ; Song Daoling[21] ; Su Zhetan[21] ; Chen Shuxun [22] ; Shen Zuofu[22] ; Jia Guoliang [23] ; Li Lansun[23] ; Jin Lan[24] ; Zhu Wenling[24] ; Ning Peiy u[25] ; Gao Yan[25] ; Lu Zhenfang [26] ; Li Yanlin[26] ; Du Xueping[27] ; Ji Guilan[27] ; Liu Yong nian[28] ; Yu Jiaju[28] ; Wang Wenbin[29] ; Li Xuerong[29] ; Hu Zhenxiang [30] ; Zheng Zhigang[30] ; Luo Beijie[31] ; Huang Dangshen[31] ; Li Changyu[32] ; Lu Huasheng[32] ; Tang Bang xi[33] ; Wang Juny ing[33] ; Liu Ruiyun[34] ; Wei Jinhan[34] ; Jiang Yuansong [35] ; Sun Peili[35] ; Shi Xiangyun[36] ; Xiong Jianran[36] ; Deng Chong xin[37] ; Zhao Yingjun[37] ;
机构： [1]FuWai Hospital, CAMS & PUMC [2]Beijing Emerg ency Medical Center [3]Dezhou Hospital [4]The First Affiliated Hospital, Chinese Medical University [5]The Third Affilia ted Hospital , Beijing Medical University [6]General Hospital, Tianjin Medical Univesity [7]Nanjing First Hospital [8]Harbin First Hospital [9]The First Affiliated Hospital, Harbin Medical University [10]Beijing Friendship Hospital [11]Shenyang General Hospital, PLA [12]Beijing Red Gross Chao Yang Hospital [13]Beijing An Zhen Hospital [14]General Hospital, PLA [15]The First Affiliated Ho spital Shanxi Medical University [16]Beijing Xuan Wu Hospital [17]Beijing Ji Shui Tan Hospital [18]Jin Zhou First Hospital [19]To ng Ji Ho spital, Tong Ji Medical University [20]Tianjin Railway Central Hospital [21]The First Affiliated Hospital, Dalian Medical University [22]Tianjin Chest Hospital [23]Xijing Affiliated Hospital, the Four th Military Medical University [24]Peking Union Medical College Hospital , CAMS & PUMC [25]Bethune International Peace Hospital [26]Tiedong Hospital, Anshan Steel and Iron Compancy [27]Beijing Fu Xing Hospital [28]Beijing Building Engineering General Hospital [29]Langfang Hospital [30]China-Japan Friendship Hospital [31]304 Hospital , PLA [32]The Second Affiliated Hospital, Dalian Medical University [33]Beijing Post- Telecon General Hospital [34]The First Affiliated Hospital, Henan Medical University [35]Yantai Yu Huang Ding Hospital [36]Navy General Hospital , PLA [37]Liaoning Province People Hospital
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摘要：
Objective To study the effects of patency of infarct-related coronary artery on acute outcome in cases of acute myocardial infarction undergoing urokinase therapy. Methods One thousand one hundred and thirty-eight cases of acute myocardial infarction admitted in 37 collaborative hospitals were given urokinase intravenously with a standard program. Patency of infarct-related coronary artery assessed by uniform criteria occurred in 757 patients (66.5%) and non-patency in 381 patients (33.5%). Four-week mortality and frequency of various severe complications were compared between patency patients and non-patency patients. Results The 4-week mortality in patients with patency was 3.4% versus 21.8% in those without patency (P < 0.001). Frequencies of various severe complications such as heart failure, shock, ventricular fibrillation, bundle branch blocks and mechanical complications (P < 0.01), and complete atrioventricular block (P < 0.05) were much higher in patients without than in those with patency. In large sized infarcts such as high lateral plus anterior wall infarction the difference in 4 week mortality was even more obvious between patients with and without patency (2.6% vs 32.7%, P < 0.001). Using Cox proportional hazards regression model analysis, patency of infarct-related coronary artery was defined as the most important independent predictor of 4-week mortality. The risk ratio for occluded versus parent infarct-related coronary artery was 6.69. Conclusion On univariate and multivariate analyses, patency of the infarct-related coronary artery was the most important prognostic factor for acute outcome in acute myocardial infarction.

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最新[2023]版：
大类 | 3 区 医学
小类 | 3 区 医学：内科
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出版当年[1995]版：
无
最新[2023]版：
Q1 MEDICINE, GENERAL & INTERNAL

影响因子： 最新[2023版] 最新五年平均 出版当年[1995版] 出版当年五年平均 出版前一年[1994版]

第一作者：
第一作者机构： [1]FuWai Hospital, CAMS & PUMC
推荐引用方式(GB/T 7714)：
Chen Zaijia,Kou Wenrong,Xu Yishu,et al.Effects of patency of infarct-related coronary artery on acute outcome in acute myocardial infarction patients undergoing urokinase therapy[J].CHINESE MEDICAL JOURNAL.1997,110(3):187-190.
APA：
Chen Zaijia,Kou Wenrong,Xu Yishu,Zhang Guozhu,Wang Yiping...&Zhao Yingjun.(1997).Effects of patency of infarct-related coronary artery on acute outcome in acute myocardial infarction patients undergoing urokinase therapy.CHINESE MEDICAL JOURNAL,110,(3)
MLA：
Chen Zaijia,et al."Effects of patency of infarct-related coronary artery on acute outcome in acute myocardial infarction patients undergoing urokinase therapy".CHINESE MEDICAL JOURNAL 110..3(1997):187-190

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