个人科研网厅 | | 帮助
首都医科大学宣武医院知识库
高级检索
当前位置： 首页 > 详情页

Influence of different starting time of urokinase therapy after acute myocardial infarction on efficacy of thrombolysis

| 认领 | 导出 |

文献详情

资源类型：
WOS体系：

收录情况： ◇ SCIE ◇ CPCI(ISTP) ◇ 中华系列

作者：
Chen Zaijia[1,*1] * ; Kou Wwenrong[1] ; Xu Yishu[1] ; Zhang Guojun[2] ; Wang yiping[2] ; Mu Ruiqi[3] ; Du Ming[3] ; Chen Changxi[4] ; Huang Jianqun[4] ; Guo Jingxuan[5] ; Ge Kanyi[5] ; Shi jialing[6] ; Sun Yuemin[6] ; Duan Baoxiang[7] ; Gong Hehe[7] ; Li Guijun[8] ; Wang Lemin[8] ; Huang Yonglin[9] ; Fu lu[9] ; Shen Luhua[10] ; Yang jiasheng[10] ; Tong Ming[11] ; Hu Xiaoling[11] ; Liu Ruiyun[12] ; Cun Zhicheng[12] ; Wu Xuesi[13] ; Chen Zhan[13] ; Li Tiande[14] ; Gai Luyu[14] ; Li Yunqian[15] ; Liu Zhoumin[15] ; Shi Shuying[16] ; Tang Zhe[16] ; Gao Binxin[17] ; Liu Zhaoxi[17] ; Li Yan[18] ; Zhang Juxia[18] ; Zhao Huayue[19] ; Wang Lin[19] ; Wang Shiguang[20] ; Chi Chuanfu[20] ; Song Daoling[21] ; Su Zhentan[21] ; Chen Shuxun[22] ; Shen Zoufu[22] ; Jia Guoliang[23] ; Li Lansun[23] ; Jin Lan[24] ; Zhu Wenling[24] ; Ning Pwiyu[25] ; Gao yan[25] ; Lu Zhenfang[26] ; Li yanlin[26] ; Du Xueping[27] ; Ji Guilan[27] ; Liu Yongnian[28] ; Yu Jiaju[28] ; Wang Wenbin[29] ; Li Xuerong[29] ; Hu Zhenxiang[30] ; Zheng Zhigang[30] ; Luo Beijie[31] ; Huang Dangshen[31] ; Li Changyu[32] ; Lu Huasheng[32] ; Tang Bangxi[33] ; Wang Junying[33] ; Wei Jinhan[34] ; Jiang Yuansong[35] ; Sun Peili[35] ; Shi Xiangyun[36] ; Xiong Jianran[36] ; Deng Chongxin[37] ; Zhao Yingjun[37] ;
机构： [1]Fu Wai Hospital,CAMS&PUMC [2]Beijing Emergency Medical Center [3]Dezhou Hospital [4]The First Affiliated Hospital,Chinese Medical University [5]The Third Affiliated Hospital,Beijing Medical University [6]General Hospital,Tianjin Medical University [7]Nanjing First Hospital [8]Harbin First Hospital [9]The First Affiliated Hospital,Harbin Medica University [10]Beijing Friendship Hospital [11]Shenyang General Hospital,PLA [12]Beijing Red Gross Chao Yang Hospital [13]Beijing An Zhen Hospital [14]General Hospital,PLA [15]The First Affiliated Hospital,Shanxi Medical University [16]Beijing Xuan Wu Hospital [17]Beijing Ji Shui Tan Hospital [18]Jin Zhou First Hospital [19]Tong Ji Hospital,Tong Ji Medical University [20]Tianjin Railway Central Hospital [21]The First Affiliated Hospital,Dalian Medical University [22]Tianjin Chest Hospital [23]Xijing Affiliated Hospital,The Fourth Military Medical University [24]Peking Union Medical College Hospital,CAMS&PUMC [25]Bethune International Peace Hospital [26]Tie dong Hospital,Anshan Steel and Iron Compancy [27]Beijing Fu Xing Hospital [28]Beijing Building Engineering General Hospital [29]Langfang Hospital [30]China-Japan Friendship Hospital [31]304 Hospital,PLA [32]The Second Affiliated Hospital,Dalian Medical University [33]Beijing Post-Telecon General Hospital [34]The First Affilitated Hospital,Henan Medical University [35]Yantai Yu Huang Ding Hospital [36]Navy General Hospital,PLA [37]Liaoning Province People Hospital
出处：
ISSN：

摘要：
Objective To investiagte the influence of different starting time of intravenous urokinase after onset of acute myocardial infarction on the efficacy of thrombolysis. Methods One thousand one hundred and thirty eight cases of acute myocardial infarction admitted in 37 collaborative hospitals were given intravenous urokinase with a standard program. Patency of infarct-related coronary artery was assessed by uniform clinical criteria. Patency rate and 4-week mortality in groups of different starting time of urokinase administration after acute onset were compared. Results According to the starting time of urokinase administration after acute onset, the 1138 cases were divided into 4 groups: 128 cases were within 2 hours (h), 461 within 2-4h, 434 within 4-6h and 115 within 6-12h. The patency rates were 71.9%, 70.1%, 63.6% and 40.0%, respectively and 4-week mortalities were 7.0%, 6.5%, 12.2% and 13.9%, respectively in the four groups. The differences of patency rates and 4-week mortalities between the groups within 2 hours and within 2-4 hours were not statistically significant, so these two groups were combined into one, i.e. within 4 hours. The patency rate of the group within 4 hours (70.5%) was significantly higher than those of the groups within 4-6 hours (P < 0.025) and within 6-12 hours (P < 0.001); the 4-week mortality of the former (6.6%) was obviously lower than those of the latter two (all P < 0.01). The patency rate of the group within 4-6 hours was higher (P < 0.001), than that of the group within 6-12 hours but the 4-week mortalities were not statistically different between the two groups. Conclusion Intravenous urokinase starting within 4 hours after onset of acute myocardial infarction is of the best efficacy.

语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[1996]版：
无
最新[2023]版：
大类 | 3 区 医学
小类 | 3 区 医学：内科
JCR分区：
出版当年[1995]版：
无
最新[2023]版：
Q1 MEDICINE, GENERAL & INTERNAL

影响因子： 最新[2023版] 最新五年平均 出版当年[1995版] 出版当年五年平均 出版前一年[1994版]

第一作者：
第一作者机构： [1]Fu Wai Hospital,CAMS&PUMC [*1]FU WAI HOSP,CAMS,BEIJING 100037,PEOPLES R CHINA [*1]FU WAI HOSP,CAMS,BEIJING 100037,PEOPLES R CHINA
通讯作者：
通讯机构： [*1]FU WAI HOSP,CAMS,BEIJING 100037,PEOPLES R CHINA [*1]FU WAI HOSP,CAMS,BEIJING 100037,PEOPLES R CHINA
推荐引用方式(GB/T 7714)：
Chen Zaijia,Kou Wwenrong,Xu Yishu,et al.Influence of different starting time of urokinase therapy after acute myocardial infarction on efficacy of thrombolysis[J].CHINESE MEDICAL JOURNAL.1997,110(1):47-49.
APA：
Chen Zaijia,Kou Wwenrong,Xu Yishu,Zhang Guojun,Wang yiping...&Zhao Yingjun.(1997).Influence of different starting time of urokinase therapy after acute myocardial infarction on efficacy of thrombolysis.CHINESE MEDICAL JOURNAL,110,(1)
MLA：
Chen Zaijia,et al."Influence of different starting time of urokinase therapy after acute myocardial infarction on efficacy of thrombolysis".CHINESE MEDICAL JOURNAL 110..1(1997):47-49

资源点击量：16399 今日访问量：0 总访问量：869 更新日期：2025-01-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持：重庆聚合科技有限公司 地址：北京市西城区长椿街45号宣武医院