Diffusion-weighted imaging as a part of PET/MR for small lesion detection in patients with primary abdominal and pelvic cancer, with or without TOF reconstruction technique
机构：[1]Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China核医学科[2]GE Healthcare, Beijing 100076, China[3]Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA[4]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China放射科[5]Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China
Objectives: To investigate the value of diffusion-weighted imaging (DWI) in detection of small lesions (≤ 10?mm) in patients with primary abdominal and pelvic cancer in hybrid PET/MR with or without time-of-flight (TOF) technique. Materials and methods: Twenty patients (11 females and 9 males, mean age 67.23 ± 12.90 years) with histologically confirmed primary abdominal and pelvic cancer underwent hybrid PET/MR examination. A total of 64 small lesions were included in this study, which were divided into two groups (≤ 10?mm and 10–30?mm). Visual scores of small lesion detection ability were rated by five-point ordinal scale. The visual scores and detectability of small lesions on TOF PET image, noTOF PET image, and DWI sequences of hybrid PET/MR examination with or without TOF technique were analyzed. Logistic regression model was established for analysis in the value of DWI in hybrid PET/MR examination with or without TOF technique in detection of the small lesions between two groups. Results: The visual evaluation revealed the small lesion (≤ 10?mm) visual scores of DWI (mean ± SD: 4.23 ± 1.41), TOF PET image (mean ± SD: 4.14 ± 0.89), and noTOF PET image (mean ± SD: 2.68 ± 1.13);.and the visual scores of small lesions (10–30?mm) on DWI (mean ± SD: 4.98 ± 0.15), TOF PET image (mean ± SD: 4.57 ± 0.59), and noTOF PET image (mean ± SD: 3.98 ± 1.05). The visual scores of all small lesions on DWI were higher than that on TOF PET data and noTOF PET data in both two groups (**P < 0.01). The missed diagnosis rates of small FDG avid lesions (≤ 10?mm) of DWI and noTOF PET image were 9.1% and 9.1%, respectively. However, the TOF PET-based clinical diagnosis detected all small lesions (≤ 30?mm). DWI was of great importance in detection of small lesions (≤ 10?mm) in the absence of TOF technique in PET/MR examination (**P < 0.01). DWI’s effect on detection of small lesions(10-30?mm) has shown no difference between PET/MR examinations with TOF and without TOF techniques (P > 0.05). Conclusion: DWI has significant value in the detection of small lesions (≤ 10?mm) in hybrid PET/MR examination without TOF technique for patients with primary abdominal and pelvic cancer. However, it had less detection benefits in the small lesions (≤ 10?mm) in hybrid PET/MR examination with TOF PET image. ? 2019, Springer Science+Business Media, LLC, part of Springer Nature.
第一作者机构：[1]Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
通讯作者：
通讯机构：[1]Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China[4]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China[5]Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China
推荐引用方式(GB/T 7714)：
Tianbin Song,Bixiao Cui,Hongwei Yang,et al.Diffusion-weighted imaging as a part of PET/MR for small lesion detection in patients with primary abdominal and pelvic cancer, with or without TOF reconstruction technique[J].Abdominal Radiology.2019,44(7):2639 -2647.doi:10.1007/s00261-019-01980-x.
APA：
Tianbin Song,Bixiao Cui,Hongwei Yang,Jie Ma,Dongmei Shuai...&Jie Lu.(2019).Diffusion-weighted imaging as a part of PET/MR for small lesion detection in patients with primary abdominal and pelvic cancer, with or without TOF reconstruction technique.Abdominal Radiology,44,(7)
MLA：
Tianbin Song,et al."Diffusion-weighted imaging as a part of PET/MR for small lesion detection in patients with primary abdominal and pelvic cancer, with or without TOF reconstruction technique".Abdominal Radiology 44..7(2019):2639 -2647
