机构：[1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China神经内科[2]Department of Neurobiology, Key Laboratory on Neurodegenerative Disorders of Ministry of Education, Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China神经生物学研究室衰老与再生研究中心北京市老年病医疗研究中心[3]Beijing Key Laboratory on Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing, China[4]Department of Neurology, Neurobiology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Brain Disorders, Beijing, China神经内科老年医学科神经生物学研究室[5]Clinical Center for Parkinson’s Disease, Capital Medical University, Beijing, China[6]National Clinical Research Center for Geriatric Disorders, Beijing, China
The sequence effect (SE) is a reason contributing to freezing of gait (FOG) in Parkinson's disease (PD) patients. There is no effective treatment for the SE. The objective of the current study is to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the SE in PD patients with FOG.
28 PD patients with FOG received either real or sham 10-Hz rTMS over the supplementary motor area (SMA). The effects of rTMS on the SE, FOG, and some gait parameters were evaluated.
rTMS did not improve the SE. Real rTMS had beneficial effects on FOG and some gait parameters, and this effect lasted for at least four weeks.
High-frequency rTMS over the SMA cannot alleviate the SE in PD patients with FOG. rTMS has a long-lasting beneficial effect on FOG; however, this effect is not achieved by improving the SE but may be through improving some other gait parameters.
第一作者机构：[1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[2]Department of Neurobiology, Key Laboratory on Neurodegenerative Disorders of Ministry of Education, Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China[3]Beijing Key Laboratory on Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing, China[5]Clinical Center for Parkinson’s Disease, Capital Medical University, Beijing, China
推荐引用方式(GB/T 7714)：
Ma Jinghong,Gao Linlin,Mi Taomian,et al.Repetitive Transcranial Magnetic Stimulation Does Not Improve the Sequence Effect in Freezing of Gait.[J].PARKINSONS DISEASE.2019,2019:2196195.doi:10.1155/2019/2196195.
APA：
Ma Jinghong,Gao Linlin,Mi Taomian,Sun Junyan,Chan Piu&Wu Tao.(2019).Repetitive Transcranial Magnetic Stimulation Does Not Improve the Sequence Effect in Freezing of Gait..PARKINSONS DISEASE,2019,
MLA：
Ma Jinghong,et al."Repetitive Transcranial Magnetic Stimulation Does Not Improve the Sequence Effect in Freezing of Gait.".PARKINSONS DISEASE 2019.(2019):2196195
