Endovascular treatment (EVT) is a promising clinical technology. However, some patients with posterior circulation stroke may not be able to achieve neurological function recovery after EVT. We reviewed the recent experience on EVT to clarify the clinical and radiographic factors that contribute to optimal neurological outcomes METHODS: We analyzed 108 consecutive patients with acute posterior circulation stroke who were treated with EVT between January 2016 and December 2018. Favorable outcome was defined as modified Rankin Scale score of 0 to 3 at 3 months. We evaluated the association and predictive value of clinical and radiographic factors that contribute to good neurological outcomes. Among the 108 patients included in the study, 43 patients had a favorable clinical outcome at day 90. Univariate analysis revealed significant association of 90-day favorable outcome with baseline values of systolic blood pressure, time of stroke onset, contrast extravasation, symptomatic intracranial hemorrhage, general anesthesia, pc-aspects score and the National Institutes of Health Stroke Scale (NIHSS) score, contrast extravasation (OR5.094; 95% CI 1.22-21.261), symptomatic intracranial hemorrhage (OR 11.24; 95% CI 1.309-96.517), general anesthesia (OR 5.094; 95% CI 1.22-21.26), baseline NIHSS (OR 1.087; 95% CI 1.023-1.309) were found to be independent predictors of favorable outcome at day 90. Contrast extravasation alone could predict unfavorable clinical outcome and mortality with high specificity CONCLUSION: In this retrospective case series, contrast extravasation, symptomatic intracranial hemorrhage, general anesthesia, and baseline NIHSS score were related to favorable prognosis in posterior circulation stroke patients after EVT. Contrast extravasation was an independent and strong predictor of unfavorable clinical outcome. Copyright ? 2019. Published by Elsevier Inc.