This study aimed to identify specific factors predicting successful outcomes after percutaneous radiofrequency thermocoagulation (RFT) for Idiopathic Trigeminal neuralgia (ITN) and risk factors that were associated with inferior outcomes. We retrospectively reviewed our cohort of 1624 patients who underwent RFT for trigeminal neuralgia between January 2000 and December 2017. Demographic and clinical data including age, gender, disease duration, affected side, baseline pain score, pain distribution, history of previous surgical intervention and pain characteristics were collected and evaluated for their association with outcome using univariate and multivariate logistic regression analysis. 78.1% of patients experienced a successful outcome of RFT for ITN as pre-defined criteria. Pain characteristics and history of surgical treatment were significant predictors associated with successful outcomes in regression analysis. Multivariate analysis identified provoked episodic pain at diagnosis (OR=23.629, 95%CI: 16.316-34.219, P=0.010), mixed pain (OR=8.394, 95%CI: 5.951-11.840, P=0.011), and no history of surgical treatment (OR=2.189, 95%CI: 1.411-3.396, P=0.019) as independent predictors for successful RFT outcome. Presence of provoked episodic pain and mixed pain were significantly associated with successful outcome of RFT for ITN. Moreover, patients with ITN who underwent RFT for the first time were more likely to benefit from successful outcome. These findings should be considered when managing ITN with RFT to improve the likelihood of a successful outcome. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.