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Cognitive improvement after carotid artery stenting in patients with symptomatic internal carotid artery near-occlusion

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机构： [a]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Beijing, China [b]Department of Neurology, AnZhen Hospital, Capital Medical University, Beijing, China [c]Department of Neurology, XuanWu Hospital, Capital Medical University, Beijing, China

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关键词： Carotid stenosis Cognitions Embolic protection device Endovascular procedure Internal carotid artery diseases

摘要：

Background and purpose: To investigate the influence of carotid artery stenting (CAS) with embolic protection device (EPD) on the cognitive function of patients with near-occlusion of the cervical internal carotid artery (ICA). Methods: From February 2014 to December 2017, a total of 79 symptomatic patients were recruited in this study. Of these patients, 31 patients refused to receive CAS therapy. They were divided into the CAS group (48 patients) and the medical treatment group (31 patients). Montreal cognitive assessment (MoCA) instrument was used for the evaluation of cognitive function. The analyzed endpoints included cumulative 12 month incidence of ipsilateral ischemic cerebrovascular events and MoCA scores at 1 month and 12 months after treatment. Results: Cumulative 12 months incidence of ipsilateral ischemic cerebrovascular events was lower in patients who underwent CAS than in patients on medical treatment (P < 0.05). In CAS group, the total MoCA score, scores of attention and delayed recall at months 1 and 12 increased when compared with those at baseline (P < 0.05). In medical treatment group, the total MoCA score and attention score at month 12 decreased when compared with those at baseline (P < 0.05). In CAS group, the total MoCA score, scores of line connection test, drawing clock, attention and delayed recall were improved at 1 and 12 months when compared with medical treatment at the same time points (P < 0.05). Conclusions: CAS with EPD not only decreases the risk of ipsilateral TIA and stroke but also may improve the cognitive function of symptomatic patients with ICA near-occlusion. © 2019 Elsevier B.V.

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出版当年[2018]版：

大类 | 3 区医学

小类 | 4 区临床神经病学 4 区神经科学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区神经科学

JCR分区：

出版当年[2017]版：

Q3 NEUROSCIENCES Q3 CLINICAL NEUROLOGY

最新[2023]版：

Q1 CLINICAL NEUROLOGY Q2 NEUROSCIENCES

影响因子： 3.7 最新[2023版] 3.2 最新五年平均 2.448 出版当年[2017版] 2.536 出版当年五年平均 2.295 出版前一年[2016版] 2.651 出版后一年[2018版]

第一作者：

第一作者机构： [a]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Beijing, China [*1]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Changchun Street No 45, Beijing 100053, China.

通讯作者：

通讯机构： [a]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Beijing, China [*1]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Changchun Street No 45, Beijing 100053, China.

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