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Correlation between left ventricular myocardial strain and left ventricular geometry in healthy adults: a cardiovascular magnetic resonance-feature tracking study

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机构: [1]Department of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China [2]Department of Magnetic Resonance, the Third Medical Centre, Chinese People’s Liberation Army General Hospital, Beijing, China [3]Xiamen Zhouxin Medical Imaging Diagnostic Centre, Xiamen, China [4]Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
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关键词: Cardiovascular magnetic resonance-feature tracking Left ventricular geometry Myocardial strain

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This study was aimed to investigate the correlation between left ventricular (LV) myocardial strain and LV geometry in healthy adults using cardiovascular magnetic resonance-feature tracking (CMR-FT). 124 gender-matched healthy adults who underwent healthy checkup using CMR cine imaging were retrospectively analyzed. Peak global radial, circumferential, longitudinal strain (GRS, GCS and GLS) for left ventricle were measured. LV geometry was assessed by the ratio of LV mass (LVM) and end-diastolic volume (EDV). GRS, GCS and GLS were 34.18 ± 6.71%, − 22.17 ± 2.28%, − 14.76 ± 2.39% for men, and 33.40 ± 6.95%, − 22.49 ± 2.27%, − 15.72 ± 2.36% for women. Multiple linear regression showed that LVM/EDV was associated with decreased GLS (β = − 0.297, p = 0.005), but was not significantly associated with GRS and GCS (both p > 0.05). There was an increase in the magnitude of GRS, GCS and GLS with advancing age (β = 0.254, β = 0.466 and β = 0.313, all p < 0.05). Greater BMI was associated with decreased GRS, GCS and GLS (β = − 0.232, β = − 0. 249 and β = − 0.279, all p < 0.05). In conclusion, compared with GRS and GCS, GLS is more sensitive to assess LV concentric remodeling in healthy adults. GRS, GCS and GLS are all independently positively associated with age and negatively associated with BMI. Sex-based LV strain reference values for healthy Chinese adults are established. © 2019, Springer Nature B.V.

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出版当年[2018]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 核医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 核医学
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出版当年[2017]版:
Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

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第一作者机构: [1]Department of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China
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通讯机构: [1]Department of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China [3]Xiamen Zhouxin Medical Imaging Diagnostic Centre, Xiamen, China
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