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Predictors of vascular events after ischemic stroke: The China Ischemic Stroke Registry Study

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收录情况： ◇ SCIE

作者：

机构： [1]Institute of Neurology, WHO Collaborating Center for Research and Training in Neuroscience, Huashan Hospital, Fudan University, Shanghai , China

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DOI：

ISSN：

关键词： Ischemia Prognosis Stroke Vascular

摘要：

Background/Aims: To measure the risk of vascular event occurrence among postischemic stroke patients in mainland China. Methods: In this multicenter prospective stroke registry study, we enrolled 1,951 patients diagnosed with acute ischemic stroke. Demographic data, prestroke risk factors, severity of neurological deficits and disability graded on the National Institutes of Health Stroke Scale (NIHSS), and modified Rankin Scale scores of each patient were measured and recorded. Patients were followed up regularly for 12 months after recruitment. Clinical endpoints were defined as occurrence of vascular events or death. Results: We detected 103 cases with nonfatal vascular events and 27 cases that died of vascular events. Cumulative incidences of total vascular events, cerebrovascular events, and coronary artery diseases were 7.2, 5.0, and 1.8%, respectively, at 12 months after the initial ischemic stroke. Concomitant atherosclerotic-thrombotic diseases (HR, 1.68; 95% CI, 1.14-2.43) and baseline NIHSS (HR, 1.07; 95% CI, 1.03-1.11) were found to be the best predictors for further occurrence of a vascular event. Antiplatelet therapy (HR, 0.52; 95% CI, 0.35-0.77) is associated with a lower risk of further vascular events. Conclusion: Our study provided valuable data on prognosis of acute ischemic stroke in Chinese patients. Copyright © 2009 S. Karger AG.

语种：

中科院(CAS)分区：

出版当年[2009]版：

大类 | 3 区医学

小类 | 3 区公共卫生、环境卫生与职业卫生 4 区临床神经病学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区公共卫生、环境卫生与职业卫生 4 区临床神经病学

JCR分区：

出版当年[2008]版：

Q3 CLINICAL NEUROLOGY Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

最新[2023]版：

Q2 CLINICAL NEUROLOGY Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

影响因子： 3.2 最新[2023版] 4.3 最新五年平均 1.737 出版当年[2008版] 2.517 出版当年五年平均 2.203 出版前一年[2007版] 2.375 出版后一年[2009版]

第一作者：

第一作者机构： [1]Institute of Neurology, WHO Collaborating Center for Research and Training in Neuroscience, Huashan Hospital, Fudan University, Shanghai , China

通讯作者：

通讯机构： [1]Institute of Neurology, WHO Collaborating Center for Research and Training in Neuroscience, Huashan Hospital, Fudan University, Shanghai , China [*1]Institute of Neurology, Fudan University 12 Wulumuqi Zhong Rd., Huashan Hospital Shanghai 200040 (China)

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