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A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy

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收录情况: ◇ SCIE ◇ 统计源期刊 ◇ CSCD-C ◇ 中华系列

机构: [1]Peking Union Med Coll, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [2]Chinese Acad Med Sci, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [3]Chinese Acad Med Sci, Fuwai Hosp, Beijing 100037, Peoples R China; [4]Shenyang No Hosp, Dept Cardiol, Shenyang 110000, Liaoning, Peoples R China; [5]Chongqing Med Univ, Dept Cardiol, Peoples Hosp Chengdu 3, Med Coll Chengdu 2, Chengdu 610031, Sichuan, Peoples R China; [6]Xi An Jiao Tong Univ, Coll Med, Dept Cardiol, Affiliated Hosp 1, Xian 710061, Shaanxi, Peoples R China; [7]Zhejiang Univ, Sch Med, Dept Cardiol, Sir Run Run Shaw Hosp, Hangzhou 310016, Zhejiang, Peoples R China; [8]Chinese Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing 100853, Peoples R China; [9]Anhui Prov Hosp, Dept Cardiol, Hefei 230001, Anhui, Peoples R China; [10]Kunming Med Coll, Dept Cardiol, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China; [11]Tianjin Chest Hosp, Dept Cardiol, Tianjin 300051, Peoples R China; [12]Inner Mongolian Peoples Hosp, Dept Cardiol, Hohhot 010017, Inner Mongolia, Mongol Peo Rep; [13]Zhejiang Univ, Sch Med, Dept Cardiol, Affiliated Hosp 2, Hangzhou 310009, Zhejiang, Peoples R China; [14]Zhejiang Hosp, Dept Cardiol, Hangzhou 310030, Zhejiang, Peoples R China; [15]Nanjing Univ, Sch Med, Dept Cardiol, Affiliated Drum Tower Hosp, Nanjing 210008, Jiangsu, Peoples R China; [16]Sun Yat Sen Univ, Dept Cardiol, Sun Yat Sun Mem Hosp, Guangzhou 510120, Guangdong, Peoples R China; [17]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing 100029, Peoples R China; [18]Beijing Inst Heart Lung & Blood Vessel Dis, Beijing 100029, Peoples R China; [19]Shanghai Jiao Tong Univ, Sch Med, Dept Cardiol, Shanghai Peoples Hosp 1, Shanghai 200080, Peoples R China; [20]Peking Union Med Coll, Dept Cardiol, Cardiovasc Inst, 167 Beilishi Rd, Beijing 100037, Peoples R China
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关键词: heart failure cardiac resynchronization therapy atrioventricular interval interventricular interval timing cycle optimization echocardiography aortic velocity time integral intracardiac electrogram QuickOpt (TM)

摘要:
Background Cardiac resynchronization therapy (CRT) with biventricular pacing improves cardiac function, functional capacity and quality of life in selected patients with heart failure. The current study aimed to evaluate the efficacy of the intracardiac electrogram (IEGM)-based optimization method, QuickOpt (TM), in Chinese patients treated with CRT. Methods Aortic time velocity integrals (AVTI) achieved at the sensed atrioventricular (AV), paced AV and interventricular (VV) interval settings recommended by both QuickOpt (TM) and standard echocardiographic optimization were measured in 101 patients. Consistency and the strength of the relationship between the two timing cycle optimization methods were assessed by intra-class correlation coefficient (ICC). Results The ICC showed good agreement and correlation with what the AVTI achieved at the optimal sensed AV (ICC=0.9683 (0.9535-0.9785)), paced AV (ICC=0.9642 (0.9475-0.9757)) and VV (ICC=0.9730 (0.9602-0.9817)) interval settings determined by the two optimization methods. The average time required by echocardiographic optimization and by QuickOpt (TM) were (78.32 +/- 32.40) minutes and (1.98 +/- 1.64) minutes respectively (P<0.0001). Conclusion The QuickOpt (TM) algorithm provides a quicker, simpler and reliable alternative to the standard method for timing cycle optimization. (ClinicalTrial.gov Reference Number: NCT00918294) Chin Med J 2012;125(3):428-433

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出版当年[2011]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
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出版当年[2010]版:
Q3 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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第一作者机构: [1]Peking Union Med Coll, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [2]Chinese Acad Med Sci, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [3]Chinese Acad Med Sci, Fuwai Hosp, Beijing 100037, Peoples R China;
通讯作者:
通讯机构: [1]Peking Union Med Coll, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [2]Chinese Acad Med Sci, Dept Cardiol, Cardiovasc Inst, Beijing 100037, Peoples R China; [3]Chinese Acad Med Sci, Fuwai Hosp, Beijing 100037, Peoples R China; [20]Peking Union Med Coll, Dept Cardiol, Cardiovasc Inst, 167 Beilishi Rd, Beijing 100037, Peoples R China
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