机构：[1]Department of Neurosurgery, Longyan First Hospital, Fujian Medical University, Fujian, China[2]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 TiantanXili, Dongcheng District, Beijing 100050, China重点科室诊疗科室神经外科神经外科首都医科大学附属天坛医院[3]Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China研究所北京市神经外科研究所首都医科大学附属天坛医院[4]Department of Radiotherapy, Longyan First Hospital, FujianMedical University, Fujian, China
Microcystic meningioma (MM) is a rare subtype of intracranial meningiomas, with clinical and radiologic features not well characterized in the literature. Based on our experience, we propose a classification system of intracranial MMs. We reviewed the medical records, radiographic studies, and operative notes of a group of consecutive patients with intracranial MM. The mean age of the 69 patients was 46.8 +/- 10.6years (range, 21-75years). Three types of intracranial MMs could be identified. Type 1 MMs presented as a solid lesion, hypointense or isointense on T1WI, hyperintense on T2WI, and homogeneous or heterogeneous enhancement, and were found in 43 patients (67.2%). Type 2 MMs represented signals similar to CSF both on T1WI and T2WI, and faint reticular enhancement with marginal enhancement, and these were found in 7 patients (10.9%). Type 3 MMs consisted of cystic-solid or cystic lesion and were found in 14 patients (21.9%). Significant differences were observed among the different types of MMs for the following variables: sex, presence of severe peritumoral brain edema (PTBE), and extent of tumor resection. Femaleswere found in all of patients with type 2 MMs, but were only 35.7% of those with type 3 MMs (P=0.018). Severe PTBEs were more common among patients with type 1 MMs (55.8%) than among those with type 2 (14.3%) and type 3 MMs (14.3%) (P=0.007). Type 1 MMs (97.7%) were associated with a significantly higher rate of gross total resection compared with the other two types (71.4 and 78.6%) (P=0.019). Total length of hospital stay after craniotomy ranged from 4 to 30days (median, 8days). There were no significant differences in progression-free survival among the three types of MMs (P=0.788). The current classification identifies three distinct types of intracranial MMbased on their radiological findings and growth patterns. The type 1 MMs are more commonly associated with severe PTBE. Type 2 and Type 3 MMs have a higher predilection towards parasaggital location with venous involvement and therefore have a lower rate of gross total resection.
第一作者机构：[1]Department of Neurosurgery, Longyan First Hospital, Fujian Medical University, Fujian, China
共同第一作者：
通讯作者：
通讯机构：[2]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 TiantanXili, Dongcheng District, Beijing 100050, China
推荐引用方式(GB/T 7714)：
Lin Zhiqin,Zhao Meng,Li Xiangrong,et al.Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas[J].NEUROSURGICAL REVIEW.2019,42(2):443-453.doi:10.1007/s10143-018-0982-9.
APA：
Lin, Zhiqin,Zhao, Meng,Li, Xiangrong,Wang, Junmei,Qiu, Ping...&Jiang, Zhongli.(2019).Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas.NEUROSURGICAL REVIEW,42,(2)
MLA：
Lin, Zhiqin,et al."Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas".NEUROSURGICAL REVIEW 42..2(2019):443-453
