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Respiratory Syncytial Virus Seasonality, Beijing, China, 2007-2015

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机构: [1]National Health Commission Key Laboratory of Systems Biology of Pathogens, Beijing, China [2]Institute of Pathogen Biology of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing [3]Capital Medical University Beijing Children’s Hospital, Beijing
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During July 2007-June 2015, we enrolled 4,225 hospitalized children with pneumonia in a study to determine the seasonality of respiratory syncytial virus (RSV) infection in Beijing, China. We defined season as the period during which >10% of total PCRs performed each week were RSV positive. We identified 8 distinctive RSV seasons. On average, the season onset occurred at week 41 (mid-October) and lasted 33 weeks, through week 20 of the next year (mid-May); 97% of all RSV-positive cases occurred during the season. RSV seasons occurred 3-5 weeks earlier and lasted weeks longer in RSV subgroup A-dominant years than in RSV subgroup B-dominant years. Our analysis indicates that monitoring such RSV subgroup shifts might provide better estimates for the onset of RSV transmission. PCR-based tests could be a flexible or complementary way of determining RSV seasonality in locations where RSV surveillance is less well-established, such as local hospitals throughout China.

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出版当年[2018]版:
大类 | 1 区 医学
小类 | 1 区 传染病学 2 区 免疫学
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 免疫学 2 区 传染病学
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出版当年[2017]版:
Q1 INFECTIOUS DISEASES Q1 IMMUNOLOGY
最新[2023]版:
Q1 IMMUNOLOGY Q1 INFECTIOUS DISEASES

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第一作者机构: [1]National Health Commission Key Laboratory of Systems Biology of Pathogens, Beijing, China [2]Institute of Pathogen Biology of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
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通讯机构: [1]National Health Commission Key Laboratory of Systems Biology of Pathogens, Beijing, China [2]Institute of Pathogen Biology of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing [*1]Institute of Pathogen Biology of Chinese Academy of Medical Sciences and Peking Union Medical College, No. 9 Dong Dan San Tiao, Dongcheng District, Beijing 100730, China
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