机构:[1]Guangdong Provincial People’s Hospital, Guangdong Province,[2]Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China,重点科室诊疗科室神经病学中心神经病学中心首都医科大学附属天坛医院[3]School of Nursing, Capital Medical University, Beijing,[4]National Clinical Research Centre for Mental Disorders and Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital and Advanced Innovation Centre for Human Brain Protection, Capital Medical University, Beijing,[5]Department of Psychiatry, University of Melbourne, Melbourne, VIC.,[6]University of Notre Dame Australia, Fremantle, WA,[7]Division of Psychiatry, School of Medicine, University of Western Australia, Perth, WA, Australia[8]Unit of Psychiatry,Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China
Aims To examine the average point prevalence of major depressive disorder in people with Type 2 diabetes and its associated factors in a comprehensive meta-analysis. Methods Two researchers independently conducted a systematic literature search of PubMed, EMBASE, PsycINFO and Cochrane databases. Studies reporting the prevalence of major depressive disorder in people with Type 2 diabetes were identified and analysed using a random-effects model. Results A total of 26 studies meeting the inclusion criteria were included in the study. The point prevalence of major depressive disorder was 14.5% (95% CI 7.9-25.3; I-2=99.65). People with Type 2 diabetes were more likely to have major depressive disorder compared with the general population (odds ratio 1.73, 95% CI 1.38-2.16). Subgroup and meta-regression analyses showed that study site, study type, diagnostic criteria and age significantly moderated the prevalence of major depressive disorder. Conclusions In this meta-analysis, the average point prevalence of major depressive disorder in people with Type 2 diabetes was high. Routine screening and more effective interventions should be implemented for this population.
基金:
University of Macau [MYRG2015-00230-FHS, MYRG2016-00005-FHS]; National Key Research and Development Programme of China [2016YFC1307200]; Beijing Municipal Administration of Hospitals Incubating Programme [PX2016028]; Beijing Municipal Administration of Hospitals' Ascent Plan [DFL20151801]
通讯机构:[8]Unit of Psychiatry,Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China
推荐引用方式(GB/T 7714):
F. Wang,S. Wang,Q.-Q. Zong,et al.Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta-analysis of comparative and epidemiological studies[J].DIABETIC MEDICINE.2019,36(8):961-969.doi:10.1111/dme.14042.
APA:
F. Wang,S. Wang,Q.-Q. Zong,Q. Zhang,C. H. Ng...&Y.-T. Xiang.(2019).Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta-analysis of comparative and epidemiological studies.DIABETIC MEDICINE,36,(8)
MLA:
F. Wang,et al."Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta-analysis of comparative and epidemiological studies".DIABETIC MEDICINE 36..8(2019):961-969