机构：[a]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University,重点科室诊疗科室神经外科神经外科首都医科大学附属天坛医院[b]China National Clinical Research Center for Neurological Diseases,[c]Beijing Key Laboratory of Learning and Cognition, School of Psychology, Capital Normal University,[d]Department of Neural reconstruction, Beijing Neurosurgery Institute, Capital Medical University,[e]School of Psychological and Cognitive Sciences, Peking University,[f]Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China,[g]Department of Psychiatry, Icahn School of Medicine at Mount Sinai,[h]Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai,[i]Friedman Brain Institute, Icahn School of Medicine at Mount Sinai[j]Department of Psychology, Queens College, The City University of New York, New York, USA
Cognitive dysfunction accompanied by neurofibromatosis type 1 is one of the significant characteristics of this neurocutaneous disorder and has a serious impact on patients' quality of life. Although studies on cognitive function in children with neurofibromatosis type 1 have revealed that attentional impairment is a key deficit in these patients, few studies have examined their neuropsychological profile, especially whether the attentional function is also abnormal and specific in adult patients with neurofibromatosis type 1. In this study, we used the revised attention network test to examine the function of three attentional networks-alerting, orienting and executive control-in 20 adult patients with neurofibromatosis type 1 in comparison to 20 normal controls. Adult patients with neurofibromatosis type 1 showed significant greater conflict effect for the executive control network, but no significant differences were found for alerting and orienting network relative to normal controls. These results provide evidence that there is an attentional deficit which is specifically associated with the executive control network in adult patients with neurofibromatosis type 1.
第一作者机构：[a]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University,[b]China National Clinical Research Center for Neurological Diseases,
共同第一作者：
通讯作者：
通讯机构：[a]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University,[b]China National Clinical Research Center for Neurological Diseases,[*1]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
推荐引用方式(GB/T 7714)：
Xingchao Wang,Qiong Wu,Hanlu Tang,et al.Selective impairment of the executive attentional network in adult patients with neurofibromatosis type 1[J].Neuroreport.2019,30(14):921-926.doi:10.1097/WNR.0000000000001275.
APA：
Xingchao Wang,Qiong Wu,Hanlu Tang,Fu Zhao,Zhijun Yang...&Pinan Liu.(2019).Selective impairment of the executive attentional network in adult patients with neurofibromatosis type 1.Neuroreport,30,(14)
MLA：
Xingchao Wang,et al."Selective impairment of the executive attentional network in adult patients with neurofibromatosis type 1".Neuroreport 30..14(2019):921-926
