机构：[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China重点科室医技科室研究所放射科放射科北京市神经外科研究所首都医科大学附属天坛医院[2]Beijing Engineering Research Center for Interventional Neuroradiology[3]Department of Interventional Cerebral Vascular, Tianjin Fifth Central Hospital, Binhai New District, Tianjin, China
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摘要：
Oculomotor nerve palsy (ONP) is commonly encountered in daily neurosurgical activities. The ONP secondary to un-ruptured PComA aneurysm might be a unique entity that was different in diagnosis, treatment and prognosis from its ruptured counterparts. Perhaps as a result of the limitation in sample size, studies that solely focused on factors affecting recovery of ONP in patients with unruptured corresponding PComA aneurysms were scarce.
In this study, we would like to report a relatively larger case series of patients with un-ruptured PComA aneurysm-related ONP. A retrospective review of medical records of 39 patients with un-ruptured PComA aneurysm-related ONP was performed with endovascular coiling.
All 39 consecutive patients underwent endovascular coiling. Eighteen (46%) patients had a complete resolution of ONP, 14 (36%) patients had a partial resolution. Time interval from onset of ONP to endovascular intervention (P=0.004), degree of ONP (P=0.015) and age (P=0.016) were predictors of ONP recovery with statistical significance. Sex, aneurysm size and risk factor exposure (smoking, alcohol abuse and hypertension) were not associated with ONP outcomes.
ONP secondary to un-ruptured aneurysm should be treated as a unique entity from its ruptured counterparts. A prospective study that contains surgical clipping and endovascular coiling, and comparison between two treatment modalities would be more convincing and is anticipated.
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外文
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出版当年[2018]版：
大类|4 区医学
小类|4 区内分泌学与代谢4 区神经科学
最新[2023]版：
大类|4 区医学
小类|4 区内分泌学与代谢4 区神经科学
第一作者：
第一作者机构：[3]Department of Interventional Cerebral Vascular, Tianjin Fifth Central Hospital, Binhai New District, Tianjin, China
通讯作者：
通讯机构：[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China[2]Beijing Engineering Research Center for Interventional Neuroradiology[*1]Beijing Neurosurgical Institute, No.6, Tiantan Xili, Dongcheng, Beijing, 100050, P.R.China
推荐引用方式(GB/T 7714)：
Su Zhiguo,Shi Wanchao,Ge Huijian,et al.Efficacy of endovascular intervention in patients with unruptured posterior communicating artery aneurysm-related oculomotor nerve palsy.[J].NEUROENDOCRINOLOGY LETTERS.2019,39(6):459-464.
APA：
Su Zhiguo,Shi Wanchao,Ge Huijian&Li Youxiang.(2019).Efficacy of endovascular intervention in patients with unruptured posterior communicating artery aneurysm-related oculomotor nerve palsy..NEUROENDOCRINOLOGY LETTERS,39,(6)
MLA：
Su Zhiguo,et al."Efficacy of endovascular intervention in patients with unruptured posterior communicating artery aneurysm-related oculomotor nerve palsy.".NEUROENDOCRINOLOGY LETTERS 39..6(2019):459-464
