国家科技重大专项(2017ZX10104001-005-010,2017ZX10103004-004)%首都卫生发展科研(首发2016-2-1142)National Science and Technology Major Project of the Ministry of Science and Technology of China(2017ZX10104001-005-010,2017ZX10103004-004)%Capital Health Research and Development of Special Projects(2016-2-1142)