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Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease

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资源类型：

收录情况： ◇ SCIE

作者：
Yonggang Ma,[1,2,3] * ; Meng Zhao,[1,2,3] * ; Qian Zhang,[1,2,3] ; Xingju Liu,[1,2,3] ; Dong Zhang,[1,2,3] ; Shuo Wang,[1,2,3] ; Yan Zhang,[1,2,3] ; Maogui Li,[1,2,3] ; Jizong Zhao[1,2,3,*1] ;
机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing [2]China National Clinical Research Center for Neurological Diseases, Beijing [3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, People’s Republic of China.
出处：
DOI： 10.1016/j.jstrokecerebrovasdis.2017.10.012
ISSN：

关键词： Moyamoya disease pediatric revascularization epilepsy outcomes

摘要：
Objective: We aimed to explore the risk factors of seizure recurrence and the optimal surgical procedure for epileptic pediatric patients with moyamoya disease (MMD). Methods: We reviewed 696 consecutive patients with MMD admitted to our hospital from 2009 to 2015. Pediatric patients with MMD who had seizures before revascularization were identified. We summarized the characteristics of seizures in pediatric patients with MMD and analyzed the predictive factors of recurrent seizure events. Results: We identified 28 pediatric patients with MMD who had seizures before revascularization. During follow-up (median 42 months), 7 patients (25.0%) experienced recurrent seizures. In the multivariate analysis, the duration of epilepsy was an independent predictor for postoperative seizure recurrences (odds ratio 3.84, 95% confidence interval 1.54-24.34; P = .035). The 2 common surgical modalities of MMD (direct and indirect bypass) had no significant difference in future seizure prevention in pediatric patients with MMD with epilepsy. Conclusions: We identified the duration of epilepsy as an independent risk factor for recurrent seizure after revascularization in pediatric patients with MMD.

基金：
"13th Five-Year Plan" National Science and Technology Supporting Plan [2015BAI12B04]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81371292]; Beijing Municipal Administration of Hospitals' Mission Plan [SML20150501]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类 | 4 区 医学
小类 | 4 区 神经科学 4 区 外周血管病
最新[2023]版：
大类 | 4 区 医学
小类 | 4 区 神经科学 4 区 外周血管病
JCR分区：
出版当年[2016]版：
Q4 PERIPHERAL VASCULAR DISEASE Q4 NEUROSCIENCES
最新[2023]版：
Q3 NEUROSCIENCES Q3 PERIPHERAL VASCULAR DISEASE

影响因子： 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

第一作者：
第一作者机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing [2]China National Clinical Research Center for Neurological Diseases, Beijing [3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, People’s Republic of China.
共同第一作者：
通讯作者：
通讯机构： [1]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing [2]China National Clinical Research Center for Neurological Diseases, Beijing [3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, People’s Republic of China. [*1]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University. No. 6 Tiantanxili, Dongcheng District, Beijing, China, 100050
推荐引用方式(GB/T 7714)：
Yonggang Ma ,Meng Zhao ,Qian Zhang ,et al.Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease[J].JOURNAL OF STROKE & CEREBROVASCULAR DISEASES.2018,27(3):740-746.doi:10.1016/j.jstrokecerebrovasdis.2017.10.012.
APA：
Yonggang Ma,,Meng Zhao,,Qian Zhang,,Xingju Liu,,Dong Zhang,...&Jizong Zhao.(2018).Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease.JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,27,(3)
MLA：
Yonggang Ma,,et al."Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease".JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 27..3(2018):740-746

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