机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China重点科室诊疗科室神经病学中心首都医科大学附属天坛医院[2]China National Clinical Research Center for Neurological Diseases, Beijing 100050, China[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, China[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China[5]Department of Neurology, Affiliated Hospital, North China University of Science and Technology, Tangshan 063000, China
We aimed to investigate the prevalence and distribution of abnormal glucose regulation, including prediabetes and newly diagnosed diabetes, according to different criteria in ischaemic stroke patients without a history of diabetes. Data were derived from a representative cohort across China. Prediabetes was defined as fasting plasma glucose (FPG) 5.6-6.9 mmol/L or 2-hour oral glucose tolerance test (OGTT) 7.8-11.0 mmol/L or haemoglobin Ale (HbAlc) 5.7-6.4%. Newly diagnosed diabetes was defined as FPG >= 7.0 mmol/L, 2h OGTT >= 11.1 mmol/L or HbAlc >= 6.5%. Among 1251 ischaemic stroke patients, 471 (37.5%) were detected as prediabetes and 539 (43.1%) were detected as newly diagnosed diabetes. Prediabetes was present in 118 (9.4%), 290 (23.2%) and 314 (25.1%) stroke patients, and newly diagnosed diabetes was present in 138 (11.0%), 370 (29.6%), and 365 (29.2%) stroke patients, based on FPG, 2 h OGTT, and HbAlc criteria, respectively. Dependency on FPG alone would have missed 74.9% of patients in the prediabetes range and 74.4% of patients in the diabetes range. Our study demonstrated a high prevalence of prediabetes and diabetes in ischaemic stroke patients without a history of diabetes. OGTT and HbAlc helped detect the majority of prediabetes and newly diagnosed diabetes in ischaemic stroke patients.
基金：
National Key Technology Research and Development Program of the Ministry of Science and Technology of the People's Republic of China [2015BAI12B04, 2015BAI12B02]; Beijing Municipal Administration of Hospitals' Mission Plan [SML20150502]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|3 区生物
小类|3 区生物工程与应用微生物4 区医学：研究与实验
最新[2023]版：
无
JCR分区：
出版当年[2016]版：
Q2BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版：
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China[2]China National Clinical Research Center for Neurological Diseases, Beijing 100050, China[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, China[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China
通讯作者：
通讯机构：[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China[2]China National Clinical Research Center for Neurological Diseases, Beijing 100050, China[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, China[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China
推荐引用方式(GB/T 7714)：
Xinmiao Zhang ,Qiuyan Shi ,Huaguang Zheng ,et al.Prevalence of Abnormal Glucose Regulation according to Different Diagnostic Criteria in Ischaemic Stroke without a History of Diabetes[J].BIOMED RESEARCH INTERNATIONAL.2018,2018:-.doi:10.1155/2018/8358724.
APA：
Xinmiao Zhang,,Qiuyan Shi,,Huaguang Zheng,,Qian Jia,,Xingquan Zhao,...&Yongjun Wang.(2018).Prevalence of Abnormal Glucose Regulation according to Different Diagnostic Criteria in Ischaemic Stroke without a History of Diabetes.BIOMED RESEARCH INTERNATIONAL,2018,
MLA：
Xinmiao Zhang,,et al."Prevalence of Abnormal Glucose Regulation according to Different Diagnostic Criteria in Ischaemic Stroke without a History of Diabetes".BIOMED RESEARCH INTERNATIONAL 2018.(2018):-
