机构:[1]Department of General Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,首都医科大学附属安贞医院[2]Editorial Office of Hepatobiliary and Pancreatic Diseases International, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China,外科系统肝胆胰外科浙江大学医学院附属第一医院[3]Department of Epidemiology and Biostatics, School of Public Health, Capital Medical University, Beijing, China
China is going through major change and the incidence of first-ever stroke has increased dramatically. In this study, we aim to determine the ultrasound characteristics of carotid intima-media thickness (CIMT) and carotid plaques (CP) in the Chinese community-based population with high risk of stroke. 1009 stroke-free participants from Datun community were classified at high risk of stroke and included in this cross-sectional study. We performed B-mode carotid ultrasound imaging in all of the study subjects to measure the CIMT in the common carotid artery (CCA) far wall and CP in the CCA, bifurcation and internal carotid artery. Stepwise logistic regression analyses were used to determine factors associated with elevated CIMT and subclinical atherosclerosis, as well as plaque burden (>= 2 plaques). Our results showed that traditional risk factors including aging, hypertension, current smoking and the level of high density lipoprotein cholesterol are associated with subclinical atherosclerosis and plaque burden in high-risk community residents. To improve primary prevention in this population, we may consider intense blood pressure and lipid management, and smoking cessation.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31672375]; Key Projects in the National Science & Technology Pillar Program [SQ2015BA1300692).]
第一作者机构:[1]Department of General Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,
共同第一作者:
通讯作者:
通讯机构:[3]Department of Epidemiology and Biostatics, School of Public Health, Capital Medical University, Beijing, China
推荐引用方式(GB/T 7714):
Lianduo Bian,Lili Xia,Yixin Wang,et al.Risk Factors of Subclinical Atherosclerosis and Plaque Burden in High Risk Individuals: Results From a Community-Based Study[J].FRONTIERS IN PHYSIOLOGY.2018,9(JUN):-.doi:10.3389/fphys.2018.00739.
APA:
Lianduo Bian,Lili Xia,Yixin Wang,Jiajia Jiang,Yonghui Zhang...&Yan He.(2018).Risk Factors of Subclinical Atherosclerosis and Plaque Burden in High Risk Individuals: Results From a Community-Based Study.FRONTIERS IN PHYSIOLOGY,9,(JUN)
MLA:
Lianduo Bian,et al."Risk Factors of Subclinical Atherosclerosis and Plaque Burden in High Risk Individuals: Results From a Community-Based Study".FRONTIERS IN PHYSIOLOGY 9..JUN(2018):-