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Risk Factors of Subclinical Atherosclerosis and Plaque Burden in High Risk Individuals: Results From a Community-Based Study

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机构: [1]Department of General Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China, [2]Editorial Office of Hepatobiliary and Pancreatic Diseases International, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China, [3]Department of Epidemiology and Biostatics, School of Public Health, Capital Medical University, Beijing, China
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关键词: carotid intima-media thickness carotid plaque plaque burden community-based study subclinical atherosclerosis

摘要:
China is going through major change and the incidence of first-ever stroke has increased dramatically. In this study, we aim to determine the ultrasound characteristics of carotid intima-media thickness (CIMT) and carotid plaques (CP) in the Chinese community-based population with high risk of stroke. 1009 stroke-free participants from Datun community were classified at high risk of stroke and included in this cross-sectional study. We performed B-mode carotid ultrasound imaging in all of the study subjects to measure the CIMT in the common carotid artery (CCA) far wall and CP in the CCA, bifurcation and internal carotid artery. Stepwise logistic regression analyses were used to determine factors associated with elevated CIMT and subclinical atherosclerosis, as well as plaque burden (>= 2 plaques). Our results showed that traditional risk factors including aging, hypertension, current smoking and the level of high density lipoprotein cholesterol are associated with subclinical atherosclerosis and plaque burden in high-risk community residents. To improve primary prevention in this population, we may consider intense blood pressure and lipid management, and smoking cessation.

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出版当年[2017]版:
大类 | 2 区 医学
小类 | 2 区 生理学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 生理学
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出版当年[2016]版:
Q1 PHYSIOLOGY
最新[2023]版:
Q2 PHYSIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

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第一作者机构: [1]Department of General Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,
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通讯机构: [3]Department of Epidemiology and Biostatics, School of Public Health, Capital Medical University, Beijing, China
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