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Primary intracranial embryonal carcinoma in children: report of two cases with review of the literature

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机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China; [2]Capital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China; [3]Gen Hosp Yangtze River Shipping, Wuhan Brain Hosp, Dept Neurosurg, Wuhan, Hubei, Peoples R China; [4]Capital Med Univ, Beijing Chaoyang Hosp, Dept Neurointervent Surg, Beijing, Peoples R China; [5]7th Hosp Baoding, Dept Neurol, Baoding 071000, Hebei, Peoples R China
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关键词: Embryonal carcinoma children germ cell tumor

摘要:
Embryonal carcinoma is a rare malignant brain tumor and stands for 5% of all intracranial germ cell tumors. Embryonal carcinoma occurs mainly in the posterior third ventricle and pineal region area. Preoperative imaging examination, blood serum and cerebrospinal fluid level of AFP and HCG can support the diagnosis. Subtotal to total removal with good preservation of the important structures can be achieved in this tumor resection. Embryonal carcinoma has poor prognosis result. Postoperative radiotherapy and adjuvant chemotherapy may increase the survival rate, but due to the malignant characteristics of the tumor the 5 years survival rate remains low. We presented two cases of embryonal carcinoma in children. Subtotal resection was achieved in these two patients; patient who had had postoperative radiotherapy and adjuvant chemotherapy had longer survival time than patient who had had surgery alone.

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中科院(CAS)分区:
出版当年[2016]版:
大类 | 4 区 医学
小类 | 4 区 肿瘤学 4 区 病理学
最新[2023]版:
JCR分区:
出版当年[2015]版:
Q3 PATHOLOGY Q4 ONCOLOGY
最新[2023]版:
Q3 PATHOLOGY Q4 ONCOLOGY Q4 PATHOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

第一作者:
第一作者机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China; [2]Capital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China;
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