Whether cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a risk factor for spontaneous intracerebral hemorrhage (ICH) and influences outcomes remains unclear. In this study, we report two cases of CADASIL presenting with cerebral hemorrhages. These cases suggest that a CADASIL vasculopathy by itself mainly results in ICH, as indicated by slight vascular risk factors and prominent neuroimaging abnormalities, suggesting that CADASIL should be considered a risk factor for ICH. Interestingly, decreased perihematomal edema was noted in ICH patients with CADASIL in this study.
基金：
Beijing Municipal Commission of Education of Science and Technology plan key projects [KM201410025028]; Capital University of Medical sciences-clinical scientific research cooperation fund [14JL54]
第一作者机构：[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100050, Peoples R China;
推荐引用方式(GB/T 7714)：
Zhang Chen,Li Wei,Li Shaowu,et al.CADASIL: two new cases with intracerebral hemorrhage[J].ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY.2017,4(4):266-271.doi:10.1002/acn3.400.
APA：
Zhang, Chen,Li, Wei,Li, Shaowu,Niu, Songtao,Wang, Xingao...&Zhang, Zaiqiang.(2017).CADASIL: two new cases with intracerebral hemorrhage.ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY,4,(4)
MLA：
Zhang, Chen,et al."CADASIL: two new cases with intracerebral hemorrhage".ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY 4..4(2017):266-271
