机构:[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tian Tan Hospital, Capital Medical University, Beijing重点科室医技科室研究所放射科放射科北京市神经外科研究所首都医科大学附属天坛医院[2]Department of Neurosurgery, Wuhan General Hospital, Guangzhou Military Command of PLA, Wuhan[3]Department of Neurosurgery, XuanWu Hospital, Capital Medical University, Beijing神经科系统神经外科首都医科大学宣武医院[4]Department of Radiology, Huashan Hospital Affiliated to Fudan University, Shanghai, China
OBJECTIVE: To evaluate the safety and efficacy of endovascular treatments, including stent-assisted coiling, of very small (<= 3 mm), ruptured intracranial aneurysms. METHODS: Ninety-three endovascularly treated patients with very small ruptured aneurysms were recruited from 4 high-volume centers between September 2010 and February 2014. Factors influencing procedural complications and outcomes were analyzed. RESULTS: Fifty-one (54.8%) aneurysms were treated by stent-assisted coiling, 41 (44.1%) by coiling alone, and 1 (1.1%) by balloon-assisted coiling. Intraprocedural or postprocedural complications occurred in 13 patients (14.0%): coil migration in 1, intraprocedural rupture in 1, hydrocephalus in 6, and ischemic event in 1. No tested factor was able to predict procedural complications. Angiographic follow-up of 67 aneurysms (72%) revealed recurrence in 5 patients (7.5%). One recurrent case was treated initially by stent-assisted coiling and the remaining four by coiling alone (P [0.044). Multivariate regression analysis showed that coiling alone was significantly associated with aneurysm recurrence (odds ratio, 13.8; 95% confidence interval, 1.1e175.3; P [0.043). CONCLUSIONS: Endovascular treatment of very small ruptured aneurysms was safe and effective and was not associated with a high rate of intraprocedural rupture. Treatment with the use of stents significantly lowered the recurrence rate without additional risks.
基金:
the National Natural Science Foundation of China (grant numbers: 81301003, 81301193, 81371315, 81471167, 81671139, and 81220108007),
National Key Research and Development Plan of China (grant number: 2016YFC1300800),
the Special Research Project for Capital Health Development (grant number 2014e1-1071).
第一作者机构:[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tian Tan Hospital, Capital Medical University, Beijing
通讯作者:
通讯机构:[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tian Tan Hospital, Capital Medical University, Beijing
推荐引用方式(GB/T 7714):
Yisen Zhang,Ming Yang,Hongqi Zhang,et al.Stent-Assisted Coiling May Prevent the Recurrence of Very Small Ruptured Intracranial Aneurysms: A Multicenter Study[J].WORLD NEUROSURGERY.2017,100:22-29.doi:10.1016/j.wneu.2016.12.107.
APA:
Yisen Zhang,Ming Yang,Hongqi Zhang,Xiaolong Zhang,Youxiang Li...&Xinjian Yang.(2017).Stent-Assisted Coiling May Prevent the Recurrence of Very Small Ruptured Intracranial Aneurysms: A Multicenter Study.WORLD NEUROSURGERY,100,
MLA:
Yisen Zhang,et al."Stent-Assisted Coiling May Prevent the Recurrence of Very Small Ruptured Intracranial Aneurysms: A Multicenter Study".WORLD NEUROSURGERY 100.(2017):22-29