Objective: This study was to evaluate the safety and efficiency of endovascular treatment of unruptured basilar tip aneurysms. Methods: We retrospectively reviewed consecutive 79 cases of unruptured basilar tip aneurysms in our center between 2009 and 2014. The patients' clinical and imaging information were recorded. Complications, initial occlusion rate, clinical outcomes and the predictors were retrospectively analyzed. Results: Thirty-five cases received conservative treatment and 44 cases were treated by endovascular embolization. In the conservative treatment group, six (19.4%) of 31 basilar tip aneurysms ruptured and resulted in five deaths (16.1%) during the mean 18.1-month follow-up (range from 1 to 60 months). Among the endovascularly treated cases, 24 (54.5%) achieved initial complete occlusion and no delayed hemorrhagic events occurred during the mean 33.6-month follow-up (range from 10 to 68 months). For 20 (45.5%) incompletely occluded cases, five postoperative or delayed hemorrhagic events and two mass effect events resulted in six deaths. There were no statistical significant differences in hemorrhagic events (p = 0.732) and mortality (p = 0.502) between the incomplete occlusion group and untreated group. Large aneurysm size (>= 10 mm) was an independent predictor for incomplete occlusion (p = 0.002), which had a potential risk of postoperative or delayed hemorrhage. On univariate analysis, initial occlusion rate and aneurysm size were found to be associated with clinical outcomes (p = 0.042 and 0.015). Conclusion: Complete occlusion for unruptured basilar tip aneurysm proved to be a safe and effective therapeutic method that could eliminate the potential risk of postoperative or delayed hemorrhage.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81471166]
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2016]版:
大类|4 区医学
小类|4 区临床神经病学4 区核医学
最新[2023]版:
大类|4 区医学
小类|4 区临床神经病学4 区核医学
JCR分区:
出版当年[2015]版:
Q4CLINICAL NEUROLOGYQ4RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q3CLINICAL NEUROLOGYQ3RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ4CLINICAL NEUROLOGY
第一作者机构:[1]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing, Peoples R China;[2]Beijing Engn Res Ctr Intervent Neuroradiol, Beijing, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing, Peoples R China;[2]Beijing Engn Res Ctr Intervent Neuroradiol, Beijing, Peoples R China;[4]Capital Med Univ, Beijing Neurosurg Inst, Beijing Tiantan Hosp, 6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Ge Huijian,Lv Xianli,Jin Hengwei,et al.The role of endovascular treatment in unruptured basilar tip aneurysms[J].INTERVENTIONAL NEURORADIOLOGY.2017,23(1):8-13.doi:10.1177/1591019916665345.
APA:
Ge, Huijian,Lv, Xianli,Jin, Hengwei,Tian, Zhihua,Li, Youxiang&He, Hongwei.(2017).The role of endovascular treatment in unruptured basilar tip aneurysms.INTERVENTIONAL NEURORADIOLOGY,23,(1)
MLA:
Ge, Huijian,et al."The role of endovascular treatment in unruptured basilar tip aneurysms".INTERVENTIONAL NEURORADIOLOGY 23..1(2017):8-13