Objective: This study aimed to assess the clinicoradiological features and treatment outcomes of intracranial dissecting aneurysms (IDAs) in childhood. Methods: We conducted a retrospective study of pediatric patients who were treated for spontaneous IDAs in our institute between January 2010 and December 2015. The clinical presentation, aneurysm characteristics, treatment modality, and outcome were studied. Results: We studied 26 pediatric patients (mean age, 13.4 years; range, 4-18 years) with 31 IDAs who comprised 6.9% of all IDA patients treated during the same period. Seventeen (65.4%) patients were males, and nine (34.6%) were females. The incidence of large (>= 10 mm in size) or giant aneurysms (>= 25 mm in size) was 65.5%. Twenty-one (80.8%) patients underwent endovascular or surgical treatment and five (19.2%) received conservative treatment. Perioperative complications occurred in three patients, in whom two eventually recovered completely with a Glasgow Outcome Scale (GOS) score of 5 and one partially recovered with a GOS score 4. Overall, 25 (96.2%) patients had a favorable outcome and one (3.8%) had an unfavorable outcome at a mean follow-up of 22.8 months (range, 6-60 months). Conclusion: Pediatric IDAs are rare. In this series, endovascular management was a relatively safe and effective method of treatment for pediatric IDAs. However, continued follow-up is required because of the possibility of aneurysm recurrence and de novo aneurysm formation after treatment.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81301003, 81371315, 81471167, 81220108007]; Special Research Project for Capital Health Development [2014-1-1071]
第一作者机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing, Peoples R China;
推荐引用方式(GB/T 7714):
Zhang Yi-Sen,Wang Shuo,Wang Yang,et al.Treatment for spontaneous intracranial Dissecting aneurysms in childhood: a retrospective study of 26 cases[J].Frontiers in Neurology.2016,7(DEC):-.doi:10.3389/fneur.2016.00224.
APA:
Zhang, Yi-Sen,Wang, Shuo,Wang, Yang,Tian, Zhong-Bin,Liu, Jian...&Yang, Xin-Jian.(2016).Treatment for spontaneous intracranial Dissecting aneurysms in childhood: a retrospective study of 26 cases.Frontiers in Neurology,7,(DEC)
MLA:
Zhang, Yi-Sen,et al."Treatment for spontaneous intracranial Dissecting aneurysms in childhood: a retrospective study of 26 cases".Frontiers in Neurology 7..DEC(2016):-