Spinal cord injury (SCI) causes a high incidence of motor and sensory dysfunctions accompanied with neuropathic pain. No effective treatment is available. Both somatosensory evoked potential (SSEP) and neuropathic pain (NPP) are transmitted via myelinated large diameter fibers of deep sensory pathways. Here we aimed to evaluate whether SSEP can consistently and objectively assess transmission of deep sensory pathways, and to examine the effects of umbilical cord mesenchymal stem cell (UCMSC) transplantation on SSEP and NPP as assessed by the pain rating index (PRI) in a patient with a 2-year history of complete cervical SCI. We demonstrate that SSEP can directly reflect physiological function of myelinated large fibers in deep sensory pathway transmission (NPP is also transmitted by the same pathway). One year after UCMSC transplantation, the SSEP parameter, PRI, and clinical presentations of NPP significantly improved.
基金：
General Hospital of Chinese People's Armed Police Forces Hospital Fund [WZ20130306]; Department of Science and Technology, Guangdong Province, China [2011A081401003]
第一作者机构：[1]Gen Hosp Chinese Peoples Armed Police Forces, Dept Cell Therapy, Beijing 100039, Peoples R China;
通讯作者：
通讯机构：[1]Gen Hosp Chinese Peoples Armed Police Forces, Dept Cell Therapy, Beijing 100039, Peoples R China;
推荐引用方式(GB/T 7714)：
Hua Rongrong,Li Ping,Wang Xiaodong,et al.Evaluation of Somatosensory Evoked Potential and Pain Rating Index in a Patient with Spinal Cord Injury Accepted Cell Therapy[J].PAIN PHYSICIAN.2016,19(4):E659-E666.
APA：
Hua, Rongrong,Li, Ping,Wang, Xiaodong,Yang, Jing,Zheng, Pei...&An, Yihua.(2016).Evaluation of Somatosensory Evoked Potential and Pain Rating Index in a Patient with Spinal Cord Injury Accepted Cell Therapy.PAIN PHYSICIAN,19,(4)
MLA：
Hua, Rongrong,et al."Evaluation of Somatosensory Evoked Potential and Pain Rating Index in a Patient with Spinal Cord Injury Accepted Cell Therapy".PAIN PHYSICIAN 19..4(2016):E659-E666
