BACKGROUND AND PURPOSE: Craniocervical artery dissection is the most common cause of ischemic stroke identified in young adults. For the diagnosis of craniocervical artery dissection, multisequence MR imaging is recommended but is time-consuming. Recently, investigators proposed a simultaneous noncontrast angiography and intraplaque hemorrhage imaging technique allowing simultaneous noncontrast MRA and vessel wall imaging in a single scan. This study sought to investigate the feasibility of 3D simultaneous noncontrast angiography and intraplaque hemorrhage MR imaging in the characterization of craniocervical artery dissection. MATERIALS AND METHODS: Twenty-four symptomatic patients (mean age, 45.0 +/- 16.1 years; 21 men) with suspected craniocervical artery dissection were recruited. The 3D simultaneous noncontrast angiography and intraplaque hemorrhage 3D TOF MRA and black-blood imaging sequences were performed on a 3T MR imaging scanner. The agreement between simultaneous noncontrast angiography and intraplaque hemorrhage imaging and multisequence MR imaging in evaluating arterial dissection was determined. RESULTS: Dissection was found to involve 1 artery in 22 patients and 2 arteries in 2 patients. The intramural hematoma and luminal occlusion were detected in 19 (79.2%) and 11 (45.8%) patients, respectively. In measuring stenosis, the Cohen kappa value between 3D TOF MRA and simultaneous noncontrast angiography and intraplaque hemorrhage imaging was 0.82 (P < .001). All intramural hematomas on multisequence imaging were successfully identified by simultaneous noncontrast angiography and intraplaque hemorrhage imaging. CONCLUSIONS: 3D simultaneous noncontrast angiography and intraplaque hemorrhage imaging showed excellent agreement with multisequence MR imaging in evaluating luminal stenosis and intramural hematoma in patients with craniocervical artery dissection. The simultaneous noncontrast angiography and intraplaque hemorrhage imaging saved nearly 50% of scanning time compared with multisequence MR imaging. Our findings suggest that 3D simultaneous noncontrast angiography and intraplaque hemorrhage imaging might be an alternative, time-efficient diagnostic tool for craniocervical artery dissection.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81271536]; Beijing Municipal Science and Technology CommissionBeijing Municipal Science & Technology Commission [D111107003111007]; Philips Healthcare
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类|3 区医学
小类|2 区神经成像2 区核医学3 区临床神经病学
最新[2025]版：
大类|2 区医学
小类|2 区核医学3 区临床神经病学3 区神经成像
JCR分区：
出版当年[2013]版：
Q1NEUROIMAGINGQ1RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ1CLINICAL NEUROLOGY
最新[2023]版：
Q1RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ2CLINICAL NEUROLOGYQ2NEUROIMAGING
第一作者机构：[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China;[3]Peoples Hosp Xinjiang Uygur Autonomous Reg, Dept Neurol, Urumqi, Peoples R China;
通讯作者：
通讯机构：[5]Tsinghua Univ, Sch Med, Ctr Biomed Imaging Res, Dept Biomed Engn, Beijing 100084, Peoples R China;[8]Tsinghua Univ, Sch Med, Ctr Biomed Imaging Res, Beijing 100084, Peoples R China
推荐引用方式(GB/T 7714)：
Li Q.,Wang J.,Chen H.,et al.Characterization of Craniocervical Artery Dissection by Simultaneous MR Noncontrast Angiography and Intraplaque Hemorrhage Imaging at 3T[J].AMERICAN JOURNAL OF NEURORADIOLOGY.2015,36(9):1769-1775.doi:10.3174/ajnr.A4348.
APA：
Li, Q.,Wang, J.,Chen, H.,Gong, X.,Ma, N....&Zhao, X. H..(2015).Characterization of Craniocervical Artery Dissection by Simultaneous MR Noncontrast Angiography and Intraplaque Hemorrhage Imaging at 3T.AMERICAN JOURNAL OF NEURORADIOLOGY,36,(9)
MLA：
Li, Q.,et al."Characterization of Craniocervical Artery Dissection by Simultaneous MR Noncontrast Angiography and Intraplaque Hemorrhage Imaging at 3T".AMERICAN JOURNAL OF NEURORADIOLOGY 36..9(2015):1769-1775
