This study aimed to evaluate the application of time- and frequency-domain analysis of heart rate variability (HRV) to screen obstructive sleep apnea-hypopnea syndrome (OSAHS) from snorers in children. Snoring children who were more than 3years old were recruited and simultaneously underwent standard polysomnography (PSG) and 24h ambulatory electrocardiography. The HRV variables of the two groups were compared, and a threshold value of the most significant variables was determined to obtain better separation power between OSAHS and non-OSAHS conditions. PSG was made as a gold standard to evaluate the capacity of HRV analysis to screen OSAHS from snorers in children. PSG results showed that 58 children manifested OSAHS and 37 were non-OSAHS snorers. LF/HFn >= 0.845 has the highest sensitivity of screening OSAHS from snorers with limited specificity, so the use of this ratio should not be overestimated.
基金：
National "Twelfth Five-Year" Science and Technology support Project [2012BAI03B02]
第一作者机构：[1]Capital Med Univ, Beijing Childrens Hosp, Beijing Pediat Res Inst, Beijing Key Lab Pediat Dis Otolaryngol Head & Nec, Beijing 100045, Peoples R China;
通讯作者：
通讯机构：[2]Capital Med Univ, Beijing Childrens Hosp, Dept Resp, Beijing 100045, Peoples R China;[4]Capital Med Univ, Beijing Childrens Hosp, Dept Resp, 56 Nanlishi Rd, Beijing 100045, Peoples R China
推荐引用方式(GB/T 7714)：
Wu Yunxiao,Xu Zhifei,Zhang Libing,et al.Screening obstructive sleep apnea-hypopnea syndrome from snorers in children by heart rate variability analysis[J].BIOLOGICAL RHYTHM RESEARCH.2015,46(2):161-171.doi:10.1080/09291016.2014.963948.
APA：
Wu, Yunxiao,Xu, Zhifei,Zhang, Libing&Shen, Kunling.(2015).Screening obstructive sleep apnea-hypopnea syndrome from snorers in children by heart rate variability analysis.BIOLOGICAL RHYTHM RESEARCH,46,(2)
MLA：
Wu, Yunxiao,et al."Screening obstructive sleep apnea-hypopnea syndrome from snorers in children by heart rate variability analysis".BIOLOGICAL RHYTHM RESEARCH 46..2(2015):161-171
