详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Large animal models of human cauda equina injury and repair: evaluation of a novel goat model

文献详情

资源类型：

收录情况： ◇ SCIE ◇ 统计源期刊 ◇ CSCD-C

作者：

机构： [1]Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100871, Peoples R China; [2]Capital Med Univ, Beijing Tian Tan Hosp, Dept Radiol, Beijing, Peoples R China

出处：

DOI：

ISSN：

关键词： nerve regeneration spinal cord injury goat animal model radiography magnetic resonance imaging diffusion tensor imaging fiber bundle diagnosis injury physiology neuroimaging NSFC grants neural regeneration

摘要：

Previous animal studies of cauda equina injury have primarily used rat models, which display significant differences from humans. Furthermore, most studies have focused on electrophysiological examination. To better mimic the outcome after surgical repair of cauda equina injury, a novel animal model was established in the goat. Electrophysiological, histological and magnetic resonance imaging methods were used to evaluate the morphological and functional outcome after cauda equina injury and end-to-end suture. Our results demonstrate successful establishment of the goat experimental model of cauda equina injury. This novel model can provide detailed information on the nerve regenerative process following surgical repair of cauda equina injury.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2014]版：

大类 | 4 区医学

小类 | 4 区细胞生物学 4 区神经科学

最新[2023]版：

大类 | 2 区医学

小类 | 3 区细胞生物学 3 区神经科学

JCR分区：

出版当年[2013]版：

Q4 CELL BIOLOGY Q4 NEUROSCIENCES

最新[2023]版：

Q1 NEUROSCIENCES Q2 CELL BIOLOGY

影响因子： 5.9 最新[2023版] 5.2 最新五年平均 0.234 出版当年[2013版] 0.169 出版当年五年平均 0.144 出版前一年[2012版] 0.22 出版后一年[2014版]

第一作者：

第一作者机构： [1]Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100871, Peoples R China;

通讯作者：

通讯机构： [1]Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100871, Peoples R China;

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]影响扩散张量图像质量和相关参数测量准确性的因素 [2]脊髓损伤的弥散张量成像研究进展 [3]Lithium promotes recovery of neurological function after spinal cord injury by inducing autophagy [4]White Matter Microstructure Alterations in Patients With Spinal Cord Injury Assessed by Diffusion Tensor Imaging [5]Brain Abnormalities in Pontine Infarction: A Longitudinal Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging study. [6]The reduction of volume and fiber bundle connections in the hippocampus of EGR3 transgenic schizophrenia rats [7]Brain Abnormalities in Pontine Infarction: A Longitudinal Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging study [8]磁共振弥散张量成像观察创伤性胼胝体损伤 [9]Evaluation of Hyperbaric Oxygen Treatment in Acute Traumatic Spinal Cord Injury in Rats Using Diffusion Tensor Imaging [10]Neural regeneration therapy after spinal cord injury induces unique brain functional reorganizations in rhesus monkeys