Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel therapy developed to treat Parkinson's disease. We report a patient who underwent bilateral DBS of the PPN and subthalamic nucleus (STN). He suffered from freezing of gait (FOG), bradykinesia, rigidity and mild tremors. The patient underwent bilateral DBS of the PPN and STN. We compared the benefits of PPN-DBS and STN-DBS using motor and gait subscores. The PPN-DBS provided modest improvements in the gait disorder and freezing episodes, while the STN-DBS failed to improve the dominant problems. This special case suggests that PPN-DBS may have a unique role in ameliorating the locomotor symptoms and has the potential to provide improvement in FOG.
第一作者机构：[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China;[2]Beijing Neurosurg Inst, Dept Stereotact & Funct Neurosurg, Beijing, Peoples R China;[3]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, 6 Tian Tan Xi Li, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Liu Huan-Guang,Zhang Kai,Yang An-Chao,et al.Deep Brain Stimulation of the Subthalamic and Pedunculopontine Nucleus in a Patient with Parkinson's Disease[J].JOURNAL OF KOREAN NEUROSURGICAL SOCIETY.2015,57(4):303-306.doi:10.3340/jkns.2015.57.4.303.
APA：
Liu, Huan-Guang,Zhang, Kai,Yang, An-Chao&Zhang, Jian-Guo.(2015).Deep Brain Stimulation of the Subthalamic and Pedunculopontine Nucleus in a Patient with Parkinson's Disease.JOURNAL OF KOREAN NEUROSURGICAL SOCIETY,57,(4)
MLA：
Liu, Huan-Guang,et al."Deep Brain Stimulation of the Subthalamic and Pedunculopontine Nucleus in a Patient with Parkinson's Disease".JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 57..4(2015):303-306
