机构:[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing, Tiantan Hospital, Capital Medical University, Beijing, China - 370453167@qq.com.重点科室医技科室研究所放射科放射科北京市神经外科研究所首都医科大学附属天坛医院
出处:
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摘要:
To compare the hemodynamic characteristics of posterior communicating artery aneurysm before and after embolization and investigate its relationship with aneurysm recurrence using a computational fluid dynamics simulation study.
Thirteen patients undergone embolization of posterior communicating artery aneurysm between January 2008 and February 2010 were enrolled and divided into recurrent and recovered group according to their follow-up angiographic data. Aneurysm models were established using three-dimensional cerebral angiography data collected before and after embolization. Preoperative and postoperative hemodynamic modalities at aneurysm neck region were analyzed with computational fluid dynamics software using the finite element algorithm. In this study, computational models were set according to transcranial Doppler pulsatile flow, and the part of aneurysm occluded by spring coil is completely independent of the blood flow.
In recurrent group, peak systolic wall shear stress and blood flow velocity at the aneurysm neck region were significant increased after the embolization. On the contrary, in recovered group peak systolic wall shear stress and blood flow velocity were significantly reduced after the embolization. The recurrent group also had higher post-embolization peak systolic wall shear stress and blood flow velocity than the recovered group.
High wall shear stress and blood flow velocity after embolization at the neck region of posterior communicating artery aneurysm may promote early aneurysm recurrence.
语种:
外文
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中科院(CAS)分区:
出版当年[2014]版:
大类|4 区医学
小类|4 区外周血管病
最新[2023]版:
大类|4 区医学
小类|4 区外周血管病
第一作者:
第一作者机构:[1]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing, Tiantan Hospital, Capital Medical University, Beijing, China - 370453167@qq.com.
推荐引用方式(GB/T 7714):
Qian Z,Kang H,Li C,et al.Effect of hemodynamics on the recurrence of posterior communicating artery aneurysm: a computational fluid dynamics simulation study.[J].INTERNATIONAL ANGIOLOGY.2015,
APA:
Qian Z,Kang H,Li C,Wu Z&Liu A.(2015).Effect of hemodynamics on the recurrence of posterior communicating artery aneurysm: a computational fluid dynamics simulation study..INTERNATIONAL ANGIOLOGY,,
MLA:
Qian Z,et al."Effect of hemodynamics on the recurrence of posterior communicating artery aneurysm: a computational fluid dynamics simulation study.".INTERNATIONAL ANGIOLOGY .(2015)