AimsTo examine the relationship between statin use in Chinese patients with intracerebral hemorrhage (ICH) during their hospitalization and the outcomes. MethodsData were collected from the China National Stroke Registry. Good functional outcome was defined by a modified Rankin Scale score between 0-2. Functional outcome and rate of mortality at 3months and 1year were compared between ICH patients on statin and those without it during their hospitalization. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated using the multivariable logistic regression model adjusted for baseline risk factors. ResultsAmong 3218 consecutive ICH patients from 2007 to 2008, 220 (6.8%) were on statin during their hospitalization. Compared with those without statin, patients on statin were younger, had more stroke risk factors but lower stroke severity. ICH patients on statin had better functional outcome at 3months (OR 2.24, 95% CI 1.49-3.36) and at 1year (OR 2.04, 95% CI 1.37-3.06). They also had lower rate of mortality at 3months (OR 0.44, 95% CI 0.22-0.87) and 1year (OR 0.49, 95% CI 0.27-0.86). ConclusionsIn-hospital statin use in ICH patients is associated with better functional outcome and lower mortality at 3months and 1year.
基金:
Ministry of Science and TechnologyMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT); Ministry of Health of the People's Republic of China [2006BA101A11, 2009CB521905]
第一作者机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China;[4]6 Tiantanxili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Pan Yue-Song,Jing Jing,Wang Yi-Long,et al.Use of Statin During Hospitalization Improves the Outcome After Intracerebral Hemorrhage[J].CNS NEUROSCIENCE & THERAPEUTICS.2014,20(6):548-555.doi:10.1111/cns.12274.
APA:
Pan, Yue-Song,Jing, Jing,Wang, Yi-Long,Zhao, Xing-Quan,Song, Bo...&Wang, Yong-Jun.(2014).Use of Statin During Hospitalization Improves the Outcome After Intracerebral Hemorrhage.CNS NEUROSCIENCE & THERAPEUTICS,20,(6)
MLA:
Pan, Yue-Song,et al."Use of Statin During Hospitalization Improves the Outcome After Intracerebral Hemorrhage".CNS NEUROSCIENCE & THERAPEUTICS 20..6(2014):548-555