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Use of Statin During Hospitalization Improves the Outcome After Intracerebral Hemorrhage

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机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [2]Zhengzhou Univ, Affiliated Hosp 1, Dept Neurol, Zhengzhou 450052, Henan Province, Peoples R China; [3]Univ Illinois, Coll Med, OSF Healthcare Syst, INI Stroke Network, Peoria, IL 61656 USA; [4]6 Tiantanxili, Beijing 100050, Peoples R China
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关键词: Hemorrhagic stroke Intracerebral hemorrhage Outcome Statin

摘要:
AimsTo examine the relationship between statin use in Chinese patients with intracerebral hemorrhage (ICH) during their hospitalization and the outcomes. MethodsData were collected from the China National Stroke Registry. Good functional outcome was defined by a modified Rankin Scale score between 0-2. Functional outcome and rate of mortality at 3months and 1year were compared between ICH patients on statin and those without it during their hospitalization. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated using the multivariable logistic regression model adjusted for baseline risk factors. ResultsAmong 3218 consecutive ICH patients from 2007 to 2008, 220 (6.8%) were on statin during their hospitalization. Compared with those without statin, patients on statin were younger, had more stroke risk factors but lower stroke severity. ICH patients on statin had better functional outcome at 3months (OR 2.24, 95% CI 1.49-3.36) and at 1year (OR 2.04, 95% CI 1.37-3.06). They also had lower rate of mortality at 3months (OR 0.44, 95% CI 0.22-0.87) and 1year (OR 0.49, 95% CI 0.27-0.86). ConclusionsIn-hospital statin use in ICH patients is associated with better functional outcome and lower mortality at 3months and 1year.

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出版当年[2013]版:
大类 | 2 区 医学
小类 | 2 区 药学 3 区 神经科学
最新[2023]版:
大类 | 1 区 医学
小类 | 2 区 神经科学 2 区 药学
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出版当年[2012]版:
Q1 NEUROSCIENCES Q1 PHARMACOLOGY & PHARMACY
最新[2023]版:
Q1 PHARMACOLOGY & PHARMACY Q1 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2012版] 出版当年五年平均 出版前一年[2011版] 出版后一年[2013版]

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第一作者机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [4]6 Tiantanxili, Beijing 100050, Peoples R China
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