Background: This meta-analysis aimed to investigate the association between type 2 diabetes (T2D) and the risk of cataract. Methods: Databases of Pubmed, Embase, and SpringerLink were retrieved for observational studies published before November 2013. The odds ratio (OR) and 95% confidence interval (CI) were used for estimating the association. All statistical analyses were performed by Stata 10.0 software. Results: A total of 8 studies involving 20837 subjects were included in the meta-analysis. The risk of any cataract (AC) in T2D patients was higher than that in non-diabetic subjects (OR = 1.97, 95% CI: 1.45-2.67, P < 0.001). The risks of cortical cataract posterior (CC) (OR = 1.68, 95% CI: 1.47-1.91, P < 0.001) and posterior subcapsular (PSC) (OR = 1.55, 95% CI: 1.27-1.90, P < 0.001) were significantly elevated in T2D patients, while no significant association was found in nuclear sclerosis (NS) (OR = 1.36, 95% CI: 0.97-1.90, P = 0.070). Conclusion: T2D patients had a higher risk of cataracts, excepting NS. Special attention should be paid on the ophthalmic extermination, especially for cataract in T2D patients.
第一作者机构:[1]Capital Med Univ, Affiliated Beijing Childrens Hosp, Dept Ophthalmol, Beijing 100045, Peoples R China;[2]Capital Med Univ, Minist Educ, Natl Key Discipline Pediat, Beijing 100045, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Affiliated Beijing Childrens Hosp, Dept Ophthalmol, Beijing 100045, Peoples R China;[2]Capital Med Univ, Minist Educ, Natl Key Discipline Pediat, Beijing 100045, Peoples R China;
推荐引用方式(GB/T 7714):
Li Li,Wan Xiu-Hua,Zhao Guo-Hong.Meta-analysis of the risk of cataract in type 2 diabetes[J].BMC OPHTHALMOLOGY.2014,14(1):-.doi:10.1186/1471-2415-14-94.
APA:
Li, Li,Wan, Xiu-Hua&Zhao, Guo-Hong.(2014).Meta-analysis of the risk of cataract in type 2 diabetes.BMC OPHTHALMOLOGY,14,(1)
MLA:
Li, Li,et al."Meta-analysis of the risk of cataract in type 2 diabetes".BMC OPHTHALMOLOGY 14..1(2014):-