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Continual Transcranial Doppler in the Monitoring of Hemodynamic Change following Aneurysmal Subarachnoid Hemorrhage

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机构: [1]Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, Beijing 100050, Peoples R China; [2]Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, 6 Tiantan Xili, Beijing 100050, Peoples R China
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关键词: Aneurysm Hemodynamics Subarachnoid hemorrhage Transcranial Doppler sonography Vasospasm

摘要:
Aims: To analyze and compare the value of different treatment methods for acute aneurysmal subarachnoid hemorrhage (aSAH)-related vasospasm. Cerebral hemodynamic variables changes were evaluated by transcranial Doppler (TCD) in aSAH patients within 14 days after onset. Methods: Thirty aSAH patients were enrolled in the study within 72 h after onset. Baseline CT and TCD were used for assessment. Patients were divided into three groups according to SAH severity and patients discretion: nonsurgical group, endovascular coiling, and neurosurgical clipping. TCD hemodynamic parameters were measured and Lindegaard index was calculated daily from onset to 14th day after SAH. The group mean cerebral blood velocity (MBFV) and Lindegaard index were compared using repeated measures analysis of variance (reANOVA). Least Significant Difference (LSD) test was used for post hoc comparison. All 30 patients were followed for 90 days after onset for outcome assessment. Results: The values of MBFV and Lindegaard index of anterior cerebral artery (ACA)/middle cerebral artery (MCA) from high to low is nonsurgical group, clipping and coiling (ACA: P= 0.0001/P= 0.006; MCA: P= 0.243/P= 0.317). Conclusions: These results indicate that both neurosurgical clipping and endovascular coiling management may relieve the severity of cerebral vasospasm in acute aSAH.

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出版当年[2011]版:
大类 | 3 区 医学
小类 | 3 区 神经科学 3 区 药学
最新[2023]版:
大类 | 1 区 医学
小类 | 2 区 神经科学 2 区 药学
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出版当年[2010]版:
Q1 PHARMACOLOGY & PHARMACY Q2 NEUROSCIENCES
最新[2023]版:
Q1 PHARMACOLOGY & PHARMACY Q1 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

第一作者:
第一作者机构: [1]Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, Beijing 100050, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, Beijing 100050, Peoples R China; [2]Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, 6 Tiantan Xili, Beijing 100050, Peoples R China
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