当前位置: 首页 > 详情页

Efficacy of Chuanxiong Ding Tong Herbal Formula Granule in the Treatment and Prophylactic of Migraine Patients: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial

文献详情

资源类型:

收录情况: ◇ SCIE

机构: [1]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Neurol, Beijing 100700, Peoples R China; [2]Minist Educ, Key Lab Internal Chinese Med, Beijing 100700, Peoples R China; [3]Beijing Univ Tradit Chinese Med, Beijing 100700, Peoples R China; [4]Changchun Univ Chinese Med, Affiliated Hosp, Dept Neurol, Changchun 130021, Peoples R China; [5]Capital Med Univ, Beijing Tiantan Hosp, Dept Tradit Chinese Med, Beijing 100050, Peoples R China; [6]Taian Hosp Tradit Chinese Med, Dept Neurol, Tai An 271000, Shandong, Peoples R China; [7]Xiamen Hosp Tradit Chinese Med, Dept Neurol, Xiamen 361001, Peoples R China; [8]Hubei Hosp Tradit Chinese Med, Dept Neurol, Wuhan 430061, Peoples R China; [9]Anhui Coll Tradit Chinese Med, Subsidiary Affiliated Hosp 1, Dept Neurol, Hefei 230031, Peoples R China; [10]China Acad Chinese Med Sci, Xiyuan Hosp, Dept Neurol, Beijing 100091, Peoples R China; [11]China Acad Chinese Med Sci, Beijing 100700, Peoples R China; [12]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Neurol, 5 Haiyun Cang, Beijing 100700, Peoples R China
出处:
ISSN:

摘要:
Objective. To evaluate the efficacy of traditional Chinese herbal ChuanXiong Ding Tong herbal formula granule (CXDT-HFG) for migraine patients with "the Syndrome of Liver Wind and Blood Stasis." Methods. 150 migraine patients were recruited and assigned randomly in a double-blind, placebo-controlled study to receive CXDT-HFG (n = 99) plus necessary analgesics, or placebo (n = 51) plus necessary analgesics for 16 weeks (12 weeks' intervention and 4 weeks' follow up). Outcome measures included migraine days, frequency of migraine attacks, analgesics consumption for acute treatment, and the proportion of responders as well as the visual analogue scale (VAS) scores and intensity for pain. Results. Compared with the placebo group, the CXDT-HFG group showed significant reduction in migraine days and attacks frequency at week 12 and follow-up period (P < 0.05) as well as in the reduction of VAS scores at follow-up period. There was significant difference in the proportion of responders between the two groups at follow-up period (P = 0.014). However there were no significant differences between the two groups in analgesics consumption (P > 0.05). Conclusion. CXDT-HFG was more effective than placebo in decreasing days of migraine attacks, frequency, VAS scores, and relieving pain intensity for migraine patients.

基金:
语种:
被引次数:
WOS:
中科院(CAS)分区:
出版当年[2011]版:
大类 | 3 区 医学
小类 | 2 区 全科医学与补充医学
最新[2023]版:
JCR分区:
出版当年[2010]版:
Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE
最新[2023]版:

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

第一作者:
第一作者机构: [1]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Neurol, Beijing 100700, Peoples R China;
通讯作者:
通讯机构: [1]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Neurol, Beijing 100700, Peoples R China; [2]Minist Educ, Key Lab Internal Chinese Med, Beijing 100700, Peoples R China; [3]Beijing Univ Tradit Chinese Med, Beijing 100700, Peoples R China; [12]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Neurol, 5 Haiyun Cang, Beijing 100700, Peoples R China
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:16409 今日访问量:0 总访问量:869 更新日期:2025-01-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持:重庆聚合科技有限公司 地址:北京市西城区长椿街45号宣武医院