详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Diversity of pneumococcal surface protein A (PspA) and relation to sequence typing in Streptococcus pneumoniae causing invasive disease in Chinese children

文献详情

资源类型：

收录情况： ◇ SCIE

作者：

机构： [1]Capital Med Univ, Beijing Childrens Hosp, Key Lab Major Dis Children, Beijing 100045, Peoples R China; [2]Capital Med Univ, Beijing Childrens Hosp, Natl Key Discipline Pediat, Minist Educ,Beijing Pediat Res Inst, Beijing 100045, Peoples R China; [3]Lanzhou Inst Biol Prod, Lanzhou, Peoples R China; [4]Shenzhen Childrens Hosp, Shenzhen, Peoples R China; [5]Fudan Univ, Pediat Hosp, Shanghai 200433, Peoples R China; [6]China Med Univ, Shengjing Hosp Affiliated, Shenyang, Peoples R China; [7]Nanjing Childrens Hosp, Nanjing, Jiangsu, Peoples R China; [8]Tianjin Childrens Hosp, Tianjin, Peoples R China; [9]Chongqing Med Univ, Chongqing Childrens Hosp Affiliated, Chongqing, Peoples R China; [10]Yuying Childrens Hosp, Wenzhou Med Coll, Wenzhou, Peoples R China; [11]Suzhou Univ, Pediat Hosp, Suzhou 215006, Peoples R China; [12]Anhui Med Univ, Affiliated Hosp, Hefei, Anhui, Peoples R China; [13]Xinjiang Med Univ, Affiliated Hosp 1, Xinjiang, Peoples R China; [14]Capital Med Univ, Beijing Childrens Hosp, Key Lab Major Dis Children, Nan Lishi Rd, Beijing 100045, Peoples R China

出处：

DOI：

ISSN：

摘要：

The objective of this paper was to investigate the sequence types (STs) and diversity of surface antigen pneumococcal surface protein A (PspA) in 171 invasive Streptococcus pneumoniae isolates from Chinese children. A total of 171 pneumococci isolates were isolated from Chinese children with invasive pneumococcal diseases (IPD) in 11 hospitals between 2006 and 2008. The pneumococci samples were characterized by serotyping, PspA classification, and multilocus sequence typing (MLST). The PspA of these strains could be assigned to two families. The PspA family 2 was the most common (120/171, 70.1%). No PspA family 3 isolates were detected. Family 1 could be subdivided into two clades, with 42 strains in clade 1 and 9 strains in clade 2, and family 2 could be subdivided into clades 3, 4, and 5, which respectively contained 5, 21, and 14 strains. In total, 65 STs were identified, of which ST320 (30/171, 17.5%), ST271 (23/171, 13.5%), and ST876 (18/171, 10.5%) were the most common types. PspA family 2 and family 1 were dominant among pneumococcal clones isolated from Chinese children with invasive disease. The strains with the same ST always presented in the same PspA family.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2011]版：

大类 | 3 区医学

小类 | 3 区传染病学 3 区微生物学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区传染病学 3 区微生物学

JCR分区：

出版当年[2010]版：

Q2 MICROBIOLOGY Q2 INFECTIOUS DISEASES

最新[2023]版：

Q2 INFECTIOUS DISEASES Q2 MICROBIOLOGY

影响因子： 3.7 最新[2023版] 3.5 最新五年平均 2.631 出版当年[2010版] 2.655 出版当年五年平均 2.605 出版前一年[2009版] 2.859 出版后一年[2011版]

第一作者：

第一作者机构： [1]Capital Med Univ, Beijing Childrens Hosp, Key Lab Major Dis Children, Beijing 100045, Peoples R China; [2]Capital Med Univ, Beijing Childrens Hosp, Natl Key Discipline Pediat, Minist Educ,Beijing Pediat Res Inst, Beijing 100045, Peoples R China;

通讯作者：

通讯机构： [1]Capital Med Univ, Beijing Childrens Hosp, Key Lab Major Dis Children, Beijing 100045, Peoples R China; [2]Capital Med Univ, Beijing Childrens Hosp, Natl Key Discipline Pediat, Minist Educ,Beijing Pediat Res Inst, Beijing 100045, Peoples R China; [14]Capital Med Univ, Beijing Childrens Hosp, Key Lab Major Dis Children, Nan Lishi Rd, Beijing 100045, Peoples R China

推荐引用方式(GB/T 7714)：

APA：

MLA：