机构:[1]Department of Hematology, Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing, 100045, China医技科室血液中心首都医科大学附属北京儿童医院
出处:
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摘要:
To investigate the clinical manifestations, pathological characteristics and treatment of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) of the penis in children. We analyzed the clinical data of a case of PNET/EWS and reviewed relevant literature. The patient was a 5-year-old boy, admitted for penis swelling with pain for 11 months. Biopsy showed a small round cell tumor, CD99 positive by immunohistochemical staining, with EWS translocation by fluorescence in situ hybridization on molecular biological examination. The tumor was confirmed to be PNET/EWS of the penis, and disappeared after 45 weeks of chemotherapy and local radiotherapy. PNET/EWS of the penis is an extremely rare disease, with no specific clinical symptoms except penis enlargement with pain. Immunohistochemistry and molecular biological examination contribute to its diagnosis.
语种:
中文
第一作者:
第一作者机构:[1]Department of Hematology, Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing, 100045, China
推荐引用方式(GB/T 7714):
Zhang D.W,Jin M,Zhou C.J,等.[Primitive neuroectodermal tumor/Ewing's sarcoma of the penis in children: a case report and review of the literature].[J].2012,18(12):