机构：[1]Capital Med Univ, Sch Stomatol, Salivary Gland Dis Ctr, Beijing 100050, Peoples R China;[2]Capital Med Univ, Sch Stomatol, Mol Lab Gene Therapy & Tooth Regenerat, Beijing 100050, Peoples R China;[3]Inst Biotechnol, Genet Lab Dev & Dis, Beijing, Peoples R China;[4]Capital Med Univ, Tian Tan Hosp, Div Electron Microscopy, Beijing 100050, Peoples R China;[5]Capital Med Univ, Sch Basic Med Sci, Dept Biochem & Mol Biol, Beijing 100050, Peoples R China;[6]Capital Med Univ, Sch Stomatol, Salivary Gland Dis Ctr, Tian Tan Xi Li 4, Beijing 100050, Peoples R China
Salivary glands are a classic model of organ development and differentiation. Miniature pigs are considered as a unique animal model for salivary gland researchers in the fields of gene transfer, radiation damage, and functional reconstruction. However, there is little information about the development of miniature pig salivary glands. The present article was designed to study the developmental stages of salivary glands in miniature pigs using histological and ultrastructural methods. Sections from E40, E60, E80, E95 embryos, and PO pups were stained with hematoxylin-eosin, Alcian blue, or periodic acid-schiff. Selected specimens were also processed for electron microscopy. The development of the miniature pig salivary glands can be divided into five different stages that refer to the stages of the developing mouse submandibular gland. The histological characteristics of the miniature pig salivary glands at different developmental stages were synchronously verified at the ultrastructural level. Interestingly, the development of the miniature pig parotid gland trailed that of the submandibular gland by similar to 15 days. Our study provides first-hand data regarding the morphological organogenesis of salivary glands in the miniature pig and provides a foundation for further research on this model. Anat Rec, 293:1227-1239, 2010. (C) 2010 Wiley-Liss, Inc.
基金：
National Basic Research Program of ChinaNational Basic Research Program of China [2007CB947304, 2010CB944801]; Academic Human Resources Development in Institutions of Higher Learning Under the jurisdiction of Beijing Municipality [PHR20090510, 2006 ID 0301200094, KM200510025002]; Ministry of Education, ChinaMinistry of Education, China [200778]
第一作者机构：[1]Capital Med Univ, Sch Stomatol, Salivary Gland Dis Ctr, Beijing 100050, Peoples R China;[2]Capital Med Univ, Sch Stomatol, Mol Lab Gene Therapy & Tooth Regenerat, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[1]Capital Med Univ, Sch Stomatol, Salivary Gland Dis Ctr, Beijing 100050, Peoples R China;[2]Capital Med Univ, Sch Stomatol, Mol Lab Gene Therapy & Tooth Regenerat, Beijing 100050, Peoples R China;[5]Capital Med Univ, Sch Basic Med Sci, Dept Biochem & Mol Biol, Beijing 100050, Peoples R China;[6]Capital Med Univ, Sch Stomatol, Salivary Gland Dis Ctr, Tian Tan Xi Li 4, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Zhou Jian,Wang Hao,Yang Guan,et al.Histological and Ultrastructural Characterization of Developing Miniature Pig Salivary Glands[J].ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY.2010,293(7):1227-1239.doi:10.1002/ar.21153.
APA：
Zhou, Jian,Wang, Hao,Yang, Guan,Wang, Xuejiu,Sun, Yilin...&Wang, Songlin.(2010).Histological and Ultrastructural Characterization of Developing Miniature Pig Salivary Glands.ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY,293,(7)
MLA：
Zhou, Jian,et al."Histological and Ultrastructural Characterization of Developing Miniature Pig Salivary Glands".ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY 293..7(2010):1227-1239
