BACKGROUND AND PURPOSE: Patients with symptomatic atherosclerotic stenosis of the intracranial vertebrobasilar artery (VBA) have a poor prognosis, and those with coexistent intracranial and extracranial stenoses have worse outcomes despite medical therapy. Our aim was to study the long-term outcome of patients with symptomatic atherosclerotic tandem stenoses at the intracranial VBA and the vertebral artery ostium (VAO) after elective stent placement. MATERIALS AND METHODS: Ten consecutive patients (mean age, 65.3 years) with this condition underwent elective stent placement at our institution between September 2001 and December 2007. Technical Success was defined as stent placement of both VAO and intracranial VBA stenoses with complete stent coverage of the lesions, residual stenosis of <= 30%, and good antegrade blood flow. The study end point was a composite of any stroke or death within 30 days and ischemic stroke in the VBA territory after 30 days. RESULTS: Technical success was obtained in 9 of 10 patients without any stroke or death within 30 days. During a median follow-up duration of 32 months, 1 patient had a fatal ischemic stroke in the VBA territory at 4 months, and the other 9 patients were tree from stroke recurrence. Thus, the annual stroke rate in VBA territory (including any stroke or death within 30 days) was 3.8%. CONCLUSIONS: This plot study shows that elective stent placement for patients with symptomatic atherosclerotic tandem stenoses at the intracranial VBA and VAO has an acceptable long-term outcome and may be considered as an alternative to medical therapy.
基金:
Ministry of Health of the People's Republic of China [2004BA714B-7]
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2008]版:
大类|3 区医学
小类|3 区临床神经病学3 区神经成像3 区核医学
最新[2023]版:
大类|3 区医学
小类|3 区临床神经病学3 区神经成像3 区核医学
JCR分区:
出版当年[2007]版:
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ2CLINICAL NEUROLOGYQ2NEUROIMAGING
最新[2023]版:
Q1RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ2CLINICAL NEUROLOGYQ2NEUROIMAGING
第一作者机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol & Intervent Neuroradiol, Beijing 100050, Peoples R China;
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol & Intervent Neuroradiol, Beijing 100050, Peoples R China;[2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol & Intervent Neuroradiol, 6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Du B.,Wong E. H. C.,Jiang W. -J..Long-Term Outcome of Tandem Stenting for Stenoses of the Intracranial Vertebrobasilar Artery and Vertebral Ostium[J].AMERICAN JOURNAL OF NEURORADIOLOGY.2009,30(4):840-844.doi:10.3174/ajnr.A1427.
APA:
Du, B.,Wong, E. H. C.&Jiang, W. -J..(2009).Long-Term Outcome of Tandem Stenting for Stenoses of the Intracranial Vertebrobasilar Artery and Vertebral Ostium.AMERICAN JOURNAL OF NEURORADIOLOGY,30,(4)
MLA:
Du, B.,et al."Long-Term Outcome of Tandem Stenting for Stenoses of the Intracranial Vertebrobasilar Artery and Vertebral Ostium".AMERICAN JOURNAL OF NEURORADIOLOGY 30..4(2009):840-844