机构：[1]The Hematology Center of Beijing Children Hospital, Capital Medical University, Beijing, 100045, China医技科室职能科室临床流行病与循证医学中心血液中心首都医科大学附属北京儿童医院
出处：
ISSN：
摘要：
To improve the understanding of severe hypercalcemia complicated in acute lymphoblastic leukemia (ALL) with E2A-HLF fusion gene, and to explore the mechanism of pathogenesis and the relationship between the special gene translocation and severe hypercalcemia. Two patients with severe hypercalcemia complicated in ALL were reported. Two patients with E2A-HLF fusion gene, which is generated by t(17;19) (q22, p13) translocation, suffered relapse of leukemia three months after chemotherapy, and developed severe hypercalcemia. After further chemotherapy, the hypercalcemia symptoms were corrected or alleviated. Severe hypercalcemia is one of rare complications of ALL. In B cell lymphoblastic leukemia with E2A-HLF fusion gene, the fusion gene showed be closely monitored for evaluating the disease situation.
语种：
中文
第一作者：
第一作者机构：[1]The Hematology Center of Beijing Children Hospital, Capital Medical University, Beijing, 100045, China
推荐引用方式(GB/T 7714)：
Yang J,Zhou X,Wang B,等.[Severe hypercalcemia complicated in acute lymphoblastic leukemia (ALL) with E2A-HLF fusion gene: report of two cases and literature review].[J].2009,30(9):
