Diffusion- and perfusion-weighted magnetic resonance imaging (DWI and PWI) was applied for stroke diagnose in 120 acute (< 48 h) ischemic stroke patients. At hyperacute (< 6 h) stage, it is difficult to find out the infarction zone in conventional T1 or T2 image, but it is easy in DWI, apparent diffusion coefficient ( ADC) map; when at 3-6-hour stage it is also easy in PWI, cerebral blood flow (CBF) map, cerebral blood volume (CBV) map, and mean transit time (MTT) map; at acute (6-48 h) stage, DWI or PWI is more sensitive than conventional T1 or T2 image too. Combining DWI with ADC, acute and chronic infarction can be distinguished. Besides, penumbra which should be developed in meaning was used as an indication or to evaluate the therapeutic efficacy. There were two cases (< 1.5 h) that broke the model of penumbra because abnormity was found in DWI but not that in PWI, finally they recovered without any sequela. Copyright (C) 2006 Ying Han et al.
基金：
National Science Fund for Distinguished Young Scholars of ChinaNational Natural Science Foundation of ChinaNational Science Fund for Distinguished Young Scholars [60225008]; Special Project of National Grand Fundamental Research 973 Program of ChinaNational Basic Research Program of China [2002CCA03900]; National High Technology Development Program of China [2002AA234051]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [60172057, 30270403]; Science Fund for Young Scholars and Returned Visiting Scholars of Beijing Municipality
语种：
外文
WOS：
中科院(CAS)分区：
出版当年[2005]版：
无
最新[2025]版：
大类|4 区医学
小类|4 区工程：生物医学
第一作者：
第一作者机构：[1]Beijing Normal Univ, Inst Cognit Neurosci & Learning, Beijing 100875, Peoples R China;
通讯作者：
通讯机构：[1]Beijing Normal Univ, Inst Cognit Neurosci & Learning, Beijing 100875, Peoples R China;
推荐引用方式(GB/T 7714)：
Han Ying,Li Enzhong,Tian Jie,et al.The Application of Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Therapy of Acute Cerebral Infarction[J].INTERNATIONAL JOURNAL OF BIOMEDICAL IMAGING.2006,2006:-.doi:10.1155/IJBI/2006/20164.
APA：
Han, Ying,Li, Enzhong,Tian, Jie,Chen, Jian,Wang, Huifang&Dai, Jianping.(2006).The Application of Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Therapy of Acute Cerebral Infarction.INTERNATIONAL JOURNAL OF BIOMEDICAL IMAGING,2006,
MLA：
Han, Ying,et al."The Application of Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Therapy of Acute Cerebral Infarction".INTERNATIONAL JOURNAL OF BIOMEDICAL IMAGING 2006.(2006):-
