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[The association of Epstein-Barr virus with Hodgkin's lymphoma in childhood].

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收录情况: ◇ 北大核心 ◇ 中华系列

机构: [1]Department of Pathology, Beijing Children's Hospital.
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Specimens from 82 children with Hodgkin's lymphoma were studied by immunohistochemical technique for Epstein-Barr virus encoded latent membrane protein (LMP). LMP was demonstrated in 67 cases 81.7%, the positive rate for the mixed cellular subtype was 90.9%. The positive rate for the 3-5 year old group of patients was 100%, 75% for the 6-10 year old group and only 62.5% for the 11-14 year old group. These findings suggest that Epstein-Barr virus is strongly associated with Hodgkin's lymphoma, the younger the age, the stronger the association. Mixed cellular subtype of Hodgkin's lymphoma had the strongest association with Epstein-Barr virus among all subtypes.

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第一作者机构: [1]Department of Pathology, Beijing Children's Hospital.
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