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The effect of calcitonin gene-related peptide on arrhythmia caused by adenosine diphosphate and desacetyldigilanide-C in rats

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机构： [a]Department of Internal Medicine, Beijing Tian-Tan Hospital, Beijing, China [b]Beijing Neurosurgical Institute, Beijing, China

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关键词： Adenosine diphosphate Arrhythmia Calcitonin gene-related peptide Desacetyldigilanide-C

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We investigated the effect of calcitonin gene-related peptide on the arrhythmia induced by two drugs in rats. The results of our experiments have proved that calcitonin gene-related peptide could reduce the degree of atrioventricular block, protect against the attacks of sinus standstill and ventricular fibrillation produced by adenosine diphosphate, and improve restoration of sinus rhythm. Calcitonin gene-related peptide was able to eliminate sinus standstill and ventricular fibrillation resulting from administration of desacetyldigilanide-C. These results demonstrate that calcitonin gene-related peptide has strong antiarrythmic effects in experimental animals. © 1991.

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大类 | 2 区医学

小类 | 3 区心脏和心血管系统

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