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THE POLYMORPHISM OF HLA ANTIGENS IN THE CHINESE

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机构： [1]AMER RED CROSS,BLOOD SERV,BETHESDA,MD 20814; [2]SHANGHAI RED CROSS,CTR BLOOD,SHANGHAI,PEOPLES R CHINA; [3]UNIV CALIF LOS ANGELES,SCH MED,DEPT BIOMATH,LOS ANGELES,CA 90024; [4]SINO JAPANESE HOSP,BEIJING,PEOPLES R CHINA; [5]COOPER HOSP,ROBERT WOOD JOHNSON MED SCH,DEPT OBSTET & GYNECOL,CAMDEN,NJ; [6]BEIJING LUNG TUMOR INST,BEIJING,PEOPLES R CHINA; [7]XINJIANG MED COLL,WULUMUQI,PEOPLES R CHINA; [8]SICHUAN MED COLL,CHENDU,PEOPLES R CHINA; [9]BEIJING RED CROSS,CTR BLOOD,BEIJING,PEOPLES R CHINA; [10]WUHAN MED COLL,WUHAN,PEOPLES R CHINA; [11]CHINESE MED COLL,SHENYANG,PEOPLES R CHINA; [12]HOWARD UNIV HOSP,WASHINGTON,DC 20060; [13]BEIJING CHILDRENS HOSP,BEIJING,PEOPLES R CHINA; [14]US FDA,CBER,DIV BLOOD & BLOOD PROD,TRANSPLANTAT BIOL LAB,BETHESDA,MD 20014

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Remarkable differences were observed in antigen frequencies (AF), gene frequencies (GF) and haplotype frequencies (HF) when 2441 healthy Chinese individuals representing nine different ethnic groups and living in 14 different geographic locations were examined for the genetic distribution of the various HLA Class I and II markers. A sizable number of individuals of each ethnic group within each of the three major categories of the Chinese population, namely, Hans, Mongols, and Southern minorities, have been studied here, providing useful population statistics for applications such as determination of probabilities of paternity, comparisons for HLA and disease associations, and anthropologic studies. Copyright © 1988, Wiley Blackwell. All rights reserved

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第一作者机构： [1]AMER RED CROSS,BLOOD SERV,BETHESDA,MD 20814; [2]SHANGHAI RED CROSS,CTR BLOOD,SHANGHAI,PEOPLES R CHINA; [3]UNIV CALIF LOS ANGELES,SCH MED,DEPT BIOMATH,LOS ANGELES,CA 90024; [4]SINO JAPANESE HOSP,BEIJING,PEOPLES R CHINA; [5]COOPER HOSP,ROBERT WOOD JOHNSON MED SCH,DEPT OBSTET & GYNECOL,CAMDEN,NJ; [6]BEIJING LUNG TUMOR INST,BEIJING,PEOPLES R CHINA; [7]XINJIANG MED COLL,WULUMUQI,PEOPLES R CHINA; [8]SICHUAN MED COLL,CHENDU,PEOPLES R CHINA; [9]BEIJING RED CROSS,CTR BLOOD,BEIJING,PEOPLES R CHINA; [10]WUHAN MED COLL,WUHAN,PEOPLES R CHINA; [11]CHINESE MED COLL,SHENYANG,PEOPLES R CHINA; [12]HOWARD UNIV HOSP,WASHINGTON,DC 20060; [13]BEIJING CHILDRENS HOSP,BEIJING,PEOPLES R CHINA; [14]US FDA,CBER,DIV BLOOD & BLOOD PROD,TRANSPLANTAT BIOL LAB,BETHESDA,MD 20014

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