Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger
机构：[1]Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania[2]Beijing Anzhen Hospital, Capital Medical University, Beijing, China首都医科大学附属安贞医院
BACKGROUND AND OBJECTIVE: To determine the efficacy of anti-vascular endothelial growth factor (VEGF) therapy for macular edema due to central retinal vein occlusion (CRVO) in younger adults. PATIENTS AND METHODS: The outcomes of CRVO patients age 40 years or younger with baseline logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) between 1.30 (20/400 Snellen equivalent) and 0.30 (20/40 Snellen equivalent) and central retinal thickness (CRT) greater than 250 mu m were reviewed. VA and CRT were measured at baseline and months 1, 3, 6, and 12. RESULTS: Seventeen eyes of 17 young CRVO patients were included in this study. The logMAR VA improved signi.cantly from 0.64 (20/87 Snellen equivalent) to 0.14 (20/28 Snellen equivalent) 12 months following treatments (P < .001). The CRT decreased from 619 mu m +/- 238 mu m at baseline to 290 mu m +/- 34 mu m at 12 months (P < .001). CONCLUSION: Anti-VEGF injections appear to be effective for macular edema regression and vision improvement in younger adults with CRVO over 12 months of follow-up.
第一作者机构：[1]Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania[2]Beijing Anzhen Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania[*1]Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Suite 1020, 840 Walnut Street, Philadelphia, PA 19107
推荐引用方式(GB/T 7714)：
Xinxiao Gao,Anthony Obeid,Christopher M. Aderman,et al.Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger[J].OPHTHALMIC SURGERY LASERS & IMAGING RETINA.2019,50(4):E96-E104.doi:10.3928/23258160-20190401-13.
APA：
Xinxiao Gao,Anthony Obeid,Christopher M. Aderman,Ferhina S. Ali,James F. Vander...&Allen C. Ho.(2019).Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger.OPHTHALMIC SURGERY LASERS & IMAGING RETINA,50,(4)
MLA：
Xinxiao Gao,et al."Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger".OPHTHALMIC SURGERY LASERS & IMAGING RETINA 50..4(2019):E96-E104
