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Factors Associated with Low Admission Platelet Count in Adults with Acute Aortic Dissection

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收录情况： ◇ SCIE

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机构： [1]Department of Anaesthesiology, Beijing AnZhen Hospital, Capital Medical University, Beijing, China [2]Department of Cardiology surgery, Beijing AnZhen Hospital, Capital Medical University, Beijing, China [3]Department of Anaesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China

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关键词： platelet count acute aortic dissection multiple regression analysis admission

摘要：

Purpose: Platelets are crucial components of the coagulation processes, and low admission platelet count (PLC) is associated with adverse clinical outcomes in patients with Stanford type A acute aortic dissection (AAD). Methods: A total of 130 consecutive patients undergoing Stanford type A AAD surgery in Beijing Anzhen Hospital were enrolled between January 2013 and July 2014. Preoperative clinical and laboratory data from patients were collected. Multiple regression analyses were used to determine the independent factors of low admission platelets. Results: Adjusted multiple regression analysis showed that age (beta: -1.069, 95% confidence interval [CI]: -2.109, -0.029), sex (beta: -29.973, 95% CI: -56.512, -3.433), tissue factor pathway inhibitor (TFPI; beta: 0.197, 95% CI: 0.039, 0.354), fibrinogen degradation product (FDP) (beta: -0.476, 95% CI: -0.879, -0.074), and attack time (beta: 11.125, 95% CI: 7.963, 14.287) were significantly associated with admission PLC. Admission PLC increased with attack time up to the 3 days (beta: 16.2, 95% CI: 12.1, 20.2). Conclusions: We found that increasing age, male patients, patients with lower serum levels of TFPI and higher serum levels of FDP, and patients with a shorter attack time were significantly associated with lower PLC at admission. Moreover, the turning point of attack time is 3 days after the onset of dissection.

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出版当年[2018]版：

大类 | 4 区医学

小类 | 4 区心脏和心血管系统 4 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区心脏和心血管系统 4 区外科

JCR分区：

出版当年[2017]版：

Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Q4 SURGERY

最新[2023]版：

Q3 SURGERY Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子： 1.1 最新[2023版] 1.4 最新五年平均 0.94 出版当年[2017版] 0.766 出版当年五年平均 0.674 出版前一年[2016版] 1.109 出版后一年[2018版]

第一作者：

第一作者机构： [1]Department of Anaesthesiology, Beijing AnZhen Hospital, Capital Medical University, Beijing, China

通讯作者：

通讯机构： [3]Department of Anaesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China [*1]Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan, Xicheng, Beijing 100050, China

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