机构：[1]Department of Ultrasound, Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease, Beijing An Zhen Hospital, Capital Medical University, Beijing, China 医技科室综合超声科首都医科大学附属安贞医院
BackgroundIt has been reported that congenital heart disease with decreased pulmonary blood flow (CHD-DPBF) may affect postnatal lung morphogenesis and function. However, there has been a lack of information regarding the impact of CHD-DPBF on prenatal fetal lung development. MethodsFifty-four fetuses with CHD-DPBF were compared with 110 controls. Fetal lung volume (FLV) was estimated using three-dimensional ultrasonography (3D-US). Estimated fetal weight (EFW) and McGoon index (MGI) were estimated using two-dimensional ultrasonography (2D-US). ResultsFLV/EFW and MGI values measured using sonography for the CHD-DPBF group were significantly reduced compared to those of the control group (P<.05). Pearson correlation analysis indicated that the summed diameter of the right pulmonary artery and left pulmonary artery (RPA+LPA) measured by 2D-US correlated well with FLV measured by 3D-US. ConclusionsIn our study, FLV/EFW and MGI values for fetuses with CHD-DPBF tended to be decreased and FLV was associated with RPA+LPA. We concluded that CHD-DPBF might delay fetal lung development. The summed diameter of the RPA+LPA measurement could be used as an alternative to FLV for assessing fetal lung development.
基金：
Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease [BZ0308]; Basic and Clinical Research of Capital Medical University [16JL39]
第一作者机构：[1]Department of Ultrasound, Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease, Beijing An Zhen Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of Ultrasound, Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease, Beijing An Zhen Hospital, Capital Medical University, Beijing, China [*1]Department of Ultrasound, Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease, Beijing An Zhen Hospital, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714)：
Guo Yong,Liu Xiaowei,Gu Xiaoyan,et al.Fetal lung volume and pulmonary artery changes in congenital heart disease with decreased pulmonary blood flow: Quantitative ultrasound analysis[J].ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES.2018,35(1):85-89.doi:10.1111/echo.13724.
APA：
Guo, Yong,Liu, Xiaowei,Gu, Xiaoyan,Zhang, Ye,Sun, Lin&He, Yihua.(2018).Fetal lung volume and pulmonary artery changes in congenital heart disease with decreased pulmonary blood flow: Quantitative ultrasound analysis.ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES,35,(1)
MLA：
Guo, Yong,et al."Fetal lung volume and pulmonary artery changes in congenital heart disease with decreased pulmonary blood flow: Quantitative ultrasound analysis".ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES 35..1(2018):85-89
