机构：[a]Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,临床科室心脏外科中心首都医科大学附属安贞医院[b]Centre for Transplant and Renal Research, The Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.,[c]Beijing Institute of Heart, Lung and Blood Vessel Diseases,首都医科大学附属安贞医院[d]Beijing Lab for Cardiovascular Precision Medicine,[e]Beijing Aortic Disease Center, Cardiovascular Surgery Center,[f]Beijing Engineering Research Center for Vascular Prostheses, Beijing, China.
Many adult patients with congenital ventricular septal defect (VSD) also developed ascending aortic dilation, but few report the clinical features and surgical management of these patients. This study was designed to study ascending aortic dilation in adult patients with congenital VSD, and summarized the treatment experience and prognosis. To assess the clinical features and surgical management, we performed a retrospective analysis on preoperative data, intraoperative data, and postoperative data from the adult patients with congenital VSD who developed ascending aortic dilation in our institution from February 2010 to December 2016. From February 2010 to December 2016, we operated on 13 adult patients (12 males, 92.31%) with VSD who developed ascending aortic dilation. Median age was 37 (interquartile range 14) years. All patients suffered from perimembranous VSD and received surgical treatment. Their symptoms were all improved after surgery, no deaths occurred. Surgery is feasible for the ascending aortic dilation in adult patients with congenital VSD. Both proper perioperative treatment and close monitoring are required for the successful surgery.
基金：
National Key R&D Program of China [2017YFC1308000]; Capital Health Development Research Project [2018-4-2068]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81170283, 81470580]; Beijing Lab for Cardiovascular Precision Medicine [PXM2017_014226_000037]; Foundation of Beijing Outstanding Young Talent Training Program [2017000021469G254]
第一作者机构：[a]Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,[c]Beijing Institute of Heart, Lung and Blood Vessel Diseases,[d]Beijing Lab for Cardiovascular Precision Medicine,[e]Beijing Aortic Disease Center, Cardiovascular Surgery Center,[f]Beijing Engineering Research Center for Vascular Prostheses, Beijing, China.
共同第一作者：
通讯作者：
通讯机构：[a]Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China,[c]Beijing Institute of Heart, Lung and Blood Vessel Diseases,[d]Beijing Lab for Cardiovascular Precision Medicine,[e]Beijing Aortic Disease Center, Cardiovascular Surgery Center,[f]Beijing Engineering Research Center for Vascular Prostheses, Beijing, China.[*1]Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Street, Beijing 100029, China
推荐引用方式(GB/T 7714)：
Hai-Yang Li,Yuan-Fei Zhao,Lu Dai,et al.Ascending aortic dilation in adult patients with congenital ventricular septal defect An observational study[J].MEDICINE.2018,97(15):-.doi:10.1097/MD.0000000000010383.
APA：
Hai-Yang Li,Yuan-Fei Zhao,Lu Dai,Shi-Jun Xu,Hong-Jia Zhang&Wen-Jian Jiang.(2018).Ascending aortic dilation in adult patients with congenital ventricular septal defect An observational study.MEDICINE,97,(15)
MLA：
Hai-Yang Li,et al."Ascending aortic dilation in adult patients with congenital ventricular septal defect An observational study".MEDICINE 97..15(2018):-
