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Current Status and Time Trends of Oral Anticoagulation Use Among Chinese Patients With Nonvalvular Atrial Fibrillation The Chinese Atrial Fibrillation Registry Study

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机构: [1]Capital Med Univ, Beijing AnZhen Hosp, Dept Cardiol, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [2]Peking Univ, Clin Res Inst, Biostat Dept, Beijing, Peoples R China; [3]Univ Birmingham, Inst Cardiovasc Sci, City Hosp, Birmingham, W Midlands, England; [4]Capital Med Univ, Beijing AnZhen Hosp, 2 AnZhen Rd, Beijing 100029, Peoples R China
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关键词: anticoagulants atrial fibrillation China registries risk factors stroke

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Background and Purpose-Reported rates of oral anticoagulation (OAC) use have been low among Chinese patients with atrial fibrillation (AF). With improved awareness, changing guidelines, this situation may be changing over time. We aimed to explore the current status and time trends of OAC use in Beijing. Methods-We used the data set from the Chinese Atrial Fibrillation Registry (CAFR), a prospective, multicenter, hospital-based registry study involving 20 tertiary and 12 nontertiary hospitals in Beijing. A total of 11496 patients with AF were enrolled from 2011 to 2014. Results-Seven thousand nine hundred seventy-seven eligible patients were included in this ancillary study. The proportions of OAC use were 36.5% (2268/6210), 28.5% (333/1168), and 21.4% (128/599) for patients with CHA(2)DS(2)-VASc scores >= 2, 1, and 0, respectively. Persistent AF, history of stroke/transient ischemic attack/peripheral embolism, diabetes mellitus, higher body mass index, and tertiary hospital management were factors positively associated with OAC use, whereas older age, previous bleeding, hypercholesterolemia, and established coronary artery disease were factors negatively associated with OAC use. Among patients with CHADS(2) scores >= 2 and CHA(2)DS(2)-VASc scores >= 2, the proportion of OAC use increased from 31.3% to 64.5% and 30.2% to 57.7%, respectively, from 2011 to 2014. Variation in OAC use was substantial among different hospitals. Conclusions-An improvement of OAC use among Chinese patients with AF in Beijing is observed in recent years although only 36.5% of patients with CHA(2)DS(2)-VASc score >= 2 received OAC. However, variations between different hospitals were large, suggesting that better education and awareness are needed to improve efforts for stroke prevention among AF patients.

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出版当年[2015]版:
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 外周血管病
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 临床神经病学 1 区 外周血管病
JCR分区:
出版当年[2014]版:
Q1 CLINICAL NEUROLOGY Q1 PERIPHERAL VASCULAR DISEASE
最新[2023]版:
Q1 CLINICAL NEUROLOGY Q1 PERIPHERAL VASCULAR DISEASE

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]Capital Med Univ, Beijing AnZhen Hosp, Dept Cardiol, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China;
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通讯机构: [1]Capital Med Univ, Beijing AnZhen Hosp, Dept Cardiol, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [4]Capital Med Univ, Beijing AnZhen Hosp, 2 AnZhen Rd, Beijing 100029, Peoples R China
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