Percutaneous Coronary Intervention Rates and Associated Independent Predictors for Progression of Nontarget Lesions in Patients With Diabetes Mellitus After Drug-Eluting Stent Implantation
Little is known about clinically driven percutaneous coronary intervention (PCI) rates and predictors for progression of nontarget lesions in diabetic patients who have undergone drug-eluting stent (DES) implantation. We retrospectively analyzed the clinical and angiographic data of 2187 diabetic patients undergoing DES implantation. The cumulative rate of nontarget lesion PCI was 6.3% at 1 year, 14.3% at 2 years, and 19.8% at 3 years. The independent predictors of need for clinically driven PCI in patients with diabetes mellitus after DES implantation included obesity (odds ratio [OR] 2.303, 95% confidence interval [CI] 1.657-3.199, P < .001), low levels of high-density lipoprotein cholesterol (OR 1.412, 95% CI 1.114-1.789, P = .004), statin use (OR 0.669, 95% CI 0.454-0.986, P = .042), insulin use (OR 1.310, 95% CI 1.030-1.665, P = .027), and Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) score (OR 1.061, 95% CI 1.045-1.077, P < .001) at baseline PCI. These findings may facilitate prediction of the risk of repeat revascularization and improve repeat revascularization rates in diabetic patients after DES implantation.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81270285, 81100198]; National Construction Program of Key Clinical specialist facility Project; Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZY201303]
第一作者机构：[1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Dept Cardiol, Beijing An Zhen Hosp, Beijing 100029, Peoples R China;
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Dept Cardiol, Beijing An Zhen Hosp, Beijing 100029, Peoples R China;[2]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Dept Cardiol, Beijing An Zhen Hosp, Anzhen Ave, Beijing 100029, Peoples R China
推荐引用方式(GB/T 7714)：
Wang Le,Zhou Yujie,Peng Pingan,et al.Percutaneous Coronary Intervention Rates and Associated Independent Predictors for Progression of Nontarget Lesions in Patients With Diabetes Mellitus After Drug-Eluting Stent Implantation[J].ANGIOLOGY.2016,67(1):12-20.doi:10.1177/0003319715578565.
APA：
Wang, Le,Zhou, Yujie,Peng, Pingan,Xu, Xiaohan,Yang, Shiwei...&Zhao, Yingxin.(2016).Percutaneous Coronary Intervention Rates and Associated Independent Predictors for Progression of Nontarget Lesions in Patients With Diabetes Mellitus After Drug-Eluting Stent Implantation.ANGIOLOGY,67,(1)
MLA：
Wang, Le,et al."Percutaneous Coronary Intervention Rates and Associated Independent Predictors for Progression of Nontarget Lesions in Patients With Diabetes Mellitus After Drug-Eluting Stent Implantation".ANGIOLOGY 67..1(2016):12-20
