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QTc interval prolongation predicts the ablation outcome in hypertensive patients with paroxysmal atrial fibrillation

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机构: [1]Capital Med Univ, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [2]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing, Peoples R China
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关键词: Hypertension Atrial fibrillation Catheter ablation QTc interval Recurrence

摘要:
An abnormal corrected QT (QTc) interval is associated with the development of atrial fibrillation (AF). It is unclear whether QTc interval is a marker of arrhythmia recurrence after radiofrequency catheter ablation (RFCA) in patients with AF. This study sought to determine the relationship between abnormal QTc interval and the recurrence after RFCA in hypertensive patients with paroxysmal AF. Two hundred and forty-two hypertensive patients with paroxysmal AF who underwent first time RFCA were retrospectively evaluated. Baseline data and QTc before the procedure were collected. Ninety-eight patients had AF recurrence after a mean follow-up of 17.0 +/- 9.4 months. Those experiencing recurrence had a longer QTc interval than those without recurrence (429 +/- 26 vs. 419 +/- 23 ms, P = 0.004). Multivariate Cox regression analysis demonstrated the QTc interval and left atrial diameter (LAD) as independent predictors of AF recurrence. Patients with a long QTc interval were at an increased risk of AF recurrence (hazard ratio 2.757, 95% CI 1.661-4.611, P < 0.001) after adjustment for multiple factors. The QTc interval had an incremental value combined with the LAD in predicting AF recurrence after RFCA. The patients with a large LAD and a long QTc interval had a much higher AF recurrence rate compared with those with a small LAD and a non-long QTc interval (78 vs. 27%, P < 0.001). QTc interval prolongation is an independent risk factor for AF recurrence after RFCA in hypertensive patients. It provides a simple predictor for identifying the patients with hypertension likely to have AF recurrence after RFCA.

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出版当年[2014]版:
大类 | 2 区 医学
小类 | 2 区 心脏和心血管系统
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统
JCR分区:
出版当年[2013]版:
Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
最新[2023]版:
Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子: 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

第一作者:
第一作者机构: [1]Capital Med Univ, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [2]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing, Peoples R China
通讯作者:
通讯机构: [1]Capital Med Univ, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China; [2]Capital Med Univ, Dept Cardiol, Beijing Anzhen Hosp, Beijing, Peoples R China
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